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首页> 外文期刊>The journals of gerontology.Series A. Biological sciences and medical sciences >The relation of peripheral arterial disease to leg force, gait speed, and functional dependence among older adults.
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The relation of peripheral arterial disease to leg force, gait speed, and functional dependence among older adults.

机译：老年人外周血动脉疾病与腿部力量，步态速度和功能依赖性的关系。

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BACKGROUND: Atherosclerotic peripheral arterial disease (PAD), common among older adults, is associated with poor low-extremity functioning. In considering functional status, varying domains exist, including activities of daily living (ADL), instrumental activities of daily living (IADL), low-extremity mobility (LEM), and leisure and/or social activities (LSA). However, little is known about how PAD is related to functional status beyond low-extremity functioning. METHODS: A total of 1798 participants 60 years old or older was selected from the population-based National Health and Nutrition Examination Survey 1999-2002 in the United States. ADL, IADL, LSA, LEM, and general physical activities (GPA) were obtained by self-report. Peak leg force was obtained from an isokinetic dynamometer. Habitual gait speed was obtained from a 20-foot timed walk. PAD was defined as an ankle-brachial blood pressure index <0.9 in either leg. RESULTS: After multivariable adjustment, the odds ratios (ORs) for dependence in IADL, LSA, and LEM comparing participants with PAD to those without were 1.60 (95% confidence interval [CI], 1.11-2.29), 1.63 (95% CI, 1.08-2.44), and 2.29 (95% CI, 1.64-3.18), respectively. Additional adjustment of peak leg force and/or habitual gait speed diminished the relations of PAD to dependence in IADL and LSA. PAD was associated with an 18.06 Newton reduction (p =.003) in peak leg force and a 0.05 m/s reduction (p =.002) in habitual gait speed. CONCLUSION: PAD was independently associated with multiple domains of functional dependence. The association between PAD and dependence in IADL and LSA was to a large extent mediated by leg force and gait speed.
机译：背景：动脉粥样硬化性外周动脉疾病（PAD）在老年人中普遍存在，与低下肢功能不良有关。在考虑功能状态时，存在着不同的领域，包括日常生活活动（ADL），日常生活工具活动（IADL），低端活动能力（LEM）以及休闲和/或社交活动（LSA）。但是，关于PAD与下肢功能以外的功能状态之间的关系知之甚少。方法：从美国以人口为基础的1999-2002年国家健康与营养检查调查中选出1798名60岁以上的参与者。 ADL，IADL，LSA，LEM和一般体育锻炼（GPA）通过自我报告获得。从等速测功机获得峰值腿力。习惯性步态速度是从20英尺的定时步行中获得的。 PAD被定义为任一腿的踝肱血压指数<0.9。结果：经过多变量调整后，IADL，LSA和LEM中有PAD参加者与无PAD参加者的依存性比值比（OR）为1.60（95％置信区间[CI]，1.11-2.29），1.63（95％CI， 1.08-2.44）和2.29（95％CI，1.64-3.18）。腿部力量峰值和/或习惯性步态速度的其他调整减少了PAD与IADL和LSA依赖的关系。 PAD与峰值腿力降低18.06牛顿（p = .003）和习惯步态速度降低0.05 m / s（p = .002）相关。结论：PAD与功能依赖的多个域独立相关。 PAD与IADL和LSA依赖性之间的关联在很大程度上是由腿部力量和步态速度介导的。

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