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首页> 外文期刊>The journals of gerontology.Series A. Biological sciences and medical sciences >Correlation of catecholamine levels in the bed nucleus of the stria terminalis and reduced sexual behavior in middle-aged male rats.
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Correlation of catecholamine levels in the bed nucleus of the stria terminalis and reduced sexual behavior in middle-aged male rats.

机译:终端纹状体床核中儿茶酚胺水平与中年雄性大鼠性行为减少的相关性。

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摘要

The correlation between dopamine (DA) and norepinephrine (NE) levels in the bed nucleus of the stria terminalis (BNST) and male sexual behavior was examined in middle-aged rats. Male rats (18-19 months) were divided into: (a) Group MIE, consisting of rats showing mounts, intromissions, and ejaculations; (b) Group MI, composed of rats showing mounts and intromissions, but no ejaculation; and (c) Group NC, consisting of noncopulators. Young adult rats (4-5 months) displaying complete copulatory behavior were used as the control. Tissue levels of DA, NE, and DA metabolites in the BNST were measured by high-pressure liquid chromatography. DA, but not NE, levels in MIE rats were significantly lower than those in young controls. DA and NE levels in MIE rats were significantly higher than those in NC rats. These results suggest that DA and NE in the BNST might play an important role in the control of male sexual behavior in middle-aged rats.
机译:在中年大鼠中检查了纹状体终末床床核(BNST)中多巴胺(DA)和去甲肾上腺素(NE)水平与男性性行为之间的相关性。将雄性大鼠(18-19个月)分为:(a)MIE组,由表现出坐骑,内向和射精的大鼠组成; (b)MI组,由表现出坐骑和内向但不射精的大鼠组成; (c)NC组,由非交配者组成。表现出完全交配行为的幼年成年大鼠(4-5个月)用作对照。通过高压液相色谱法测量BNST中DA,NE和DA代谢物的组织水平。 MIE大鼠中的DA(而非NE)水平显着低于年轻对照组。 MIE大鼠的DA和NE水平显着高于NC大鼠。这些结果表明,BNST中的DA和NE可能在控制中年大鼠的男性性行为中起重要作用。

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