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首页> 外文期刊>The journals of gerontology.Series A. Biological sciences and medical sciences >Unintentional weight loss predicts decline in activities of daily living function and life-space mobility over 4 years among community-dwelling older adults.
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Unintentional weight loss predicts decline in activities of daily living function and life-space mobility over 4 years among community-dwelling older adults.

机译：意外体重减轻预计居住社区的老年人在4年内的日常生活功能和生活空间活动性下降。

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BACKGROUND: The relationship between body mass index (BMI), weight loss, and changes in activities of daily living (ADL) function and mobility in older adults is not clear. We sought to study the relationship between BMI and weight loss on the rate of decline in ADL function and life-space mobility over a 4-year period among older African Americans and whites. METHODS: The participants were 983 enrollees in the University of Alabama at Birmingham (UAB) Study of Aging, a longitudinal study of mobility among community-dwelling older adults stratified to achieve a balanced sample in terms of sex, race, and residence. Primary outcome measures were changes in ADL function and mobility assessed by the UAB Study of Aging Life-Space Assessment (LSA) which were measured every 6 months. RESULTS: Relative to normal weight participants, those with BMI levels in the obese range did not show more rapid ADL functional decline, but a history of unintentional weight loss predicted more rapid decline. Relative to normal-weight participants, other BMI categories were not associated with more rapid decline in LSA scores. However, unintentional weight loss predicted more rapid declines in LSA. Intentional weight loss had no relation to ADL function or LSA decline. CONCLUSIONS: In this population of community-dwelling older African Americans and whites, neither BMI nor intentional weight loss had an association with rate of functional decline. Unintentional weight loss had a negative relation with rate of functional decline, regardless of baseline BMI. Whether this is causal remains to be determined.
机译：背景：老年人的体重指数（BMI），体重减轻以及日常生活活动（ADL）功能和活动性变化之间的关系尚不清楚。我们试图研究BMI和体重减轻之间的关系，该关系在4年内针对年长的非洲裔美国人和白人的ADL功能下降率和生命空间流动性。方法：参加者为阿拉巴马大学伯明翰分校（UAB）的983位研究者，这是一项针对居住在社区的老年人流动性的纵向研究，分层后得出性别，种族和居住状况的均衡样本。主要结果指标是通过AAB老化生命空间评估（LSA）研究评估的ADL功能和活动性变化，该变化每6个月进行一次测量。结果：相对于正常体重参与者，BMI水平在肥胖范围内的参与者没有显示出更快的ADL功能下降，但是无意减肥的历史预示着下降更快。相对于体重正常的参与者，其他BMI类别与LSA分数的快速下降没有关联。但是，无意识的体重减轻预示着LSA的下降更快。故意减肥与ADL功能或LSA下降无关。结论：在这个居住在社区中的老年非裔美国人和白人人群中，BMI和故意减肥均与功能下降率无关。意外体重减轻与功能下降率呈负相关，而与基线BMI无关。这是否是因果关系尚待确定。

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