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首页> 外文期刊>The journals of gerontology.Series A. Biological sciences and medical sciences >Health span approximates life span among many supercentenarians: compression of morbidity at the approximate limit of life span.
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Health span approximates life span among many supercentenarians: compression of morbidity at the approximate limit of life span.

机译：健康寿命近似于许多超百岁老人的寿命：发病率在近似寿命极限时得到压缩。

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摘要

We analyze the relationship between age of survival, morbidity, and disability among centenarians (age 100-104 years), semisupercentenarians (age 105-109 years), and supercentenarians (age 110-119 years). One hundred and four supercentenarians, 430 semisupercentenarians, 884 centenarians, 343 nonagenarians, and 436 controls were prospectively followed for an average of 3 years (range 0-13 years). The older the age group, generally, the later the onset of diseases, such as cancer, cardiovascular disease, dementia, and stroke, as well as of cognitive and functional decline. The hazard ratios for these individual diseases became progressively less with older and older age, and the relative period of time spent with disease was lower with increasing age group. We observed a progressive delay in the age of onset of physical and cognitive function impairment, age-related diseases, and overall morbidity with increasing age. As the limit of human life span was effectively approached with supercentenarians, compression of morbidity was generally observed.
机译：我们分析了百岁老人（100-104岁），半超百岁老人（105-109岁）和超百岁老人（110-119岁）之间的生存年龄，发病率和残疾之间的关系。预期平均随访3年（范围0-13岁）的104个超级百岁老人，430个半超级百岁老人，884个百岁老人，343个非agenararians和436个对照。通常，年龄组越老，疾病如癌症，心血管疾病，痴呆和中风以及认知和功能下降的发作就越晚。这些个体疾病的危险比随着年龄的增长而逐渐降低，并且随着年龄的增长，疾病所花费的相对时间越短。我们观察到，随着年龄的增长，身体和认知功能障碍，与年龄有关的疾病以及总体发病率的发病年龄会逐渐延迟。随着超百岁老人有效地接近了人类的寿命极限，人们普遍观察到发病率的降低。

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