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首页> 外文期刊>The journals of gerontology.Series A. Biological sciences and medical sciences >The human life span is not that limited: the effect of multiple longevity phenotypes.
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The human life span is not that limited: the effect of multiple longevity phenotypes.

机译：人类的寿命没有限制：多种寿命表型的影响。

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摘要

There is an ongoing debate as to whether or not human longevity is approaching its limits. The debate and its outcome are important since they might affect public policy. We review the evidence presented by both schools. We add our empirical observation that there exist multiple longevity phenotypes, each of which arises from the alteration of fundamental aging processes. The current debate only considers two of the three known mammalian longevity phenotypes. The overlooked phenotype is the delayed onset of senescence phenotype, which can be induced by various interventions, including pharmaceuticals. The existence of multiple phenotypes means that an overview of potential life expectancy outcomes for a species should be based on the analysis of all longevity phenotypes likely to occur in that species.
机译：关于人类寿命是否正在接近极限的争论正在进行中。辩论及其结果很重要，因为它们可能会影响公共政策。我们审查了两所学校提供的证据。我们添加了经验观察，发现存在多种寿命表型，每种表型都来自基本衰老过程的改变。目前的辩论只考虑了三种已知的哺乳动物寿命表型中的两种。被忽视的表型是衰老表型的延迟发作，其可以通过包括药物在内的各种干预来诱导。多种表型的存在意味着一个物种潜在的预期寿命结果的概述应基于对该物种可能发生的所有长寿表型的分析。

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