...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The journals of gerontology.Series A. Biological sciences and medical sciences >Relationship between obesity and obesity-related morbidities weakens with aging
【24h】

Relationship between obesity and obesity-related morbidities weakens with aging

机译：肥胖与肥胖相关疾病之间的关系随着年龄的增长而减弱

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background. A weak relationship exists between obesity and mortality risk in older populations, however, the influence of age on the relationship between obesity and morbidity is unclear. The objective of this study was to determine the influence of age on the relationship between obesity and cardiovascular disease, type 2 diabetes, dyslipidemia, and hypertension. Methods. Data from the Third National Health and Nutrition Examination Survey (1988-1994) were used. Individuals were classified into specific age (young: 18-40; middle: 40-65; old: 65-75; and very old: ≥75 years) and body mass index (BMI; 18.5-24.9, 25-29.9, ≥ 30kg/m2) categories. Cardiovascular disease, type 2 diabetes, dyslipidemia, and hypertension were categorized using measured metabolic risk factors, physician diagnosis, or medication use. Results .Age modified the relationship between BMI and cardiovascular disease (Age × BMI interaction, p =.049), dyslipidemia (Age × BMI interaction, p =.035 for men, p .001 for women), and hypertension (Age × BMI interaction, p =.023) in women but not in men (p =.167). However, age did not modify the relationship between BMI and type 2 diabetes (Age × BMI interaction, p =.177). BMI was strongly associated with increased relative risk of cardiovascular disease, dyslipidemia, type 2 diabetes, and hypertension in the young and middle aged, however, the association between BMI and these metabolic conditions were much more attenuated with increasing age. Conclusion. A stronger association between obesity and prevalent metabolic conditions exists in young and middle-aged populations than in old and very old populations. Longitudinal studies are needed to verify these findings and to confirm the benefits of weight loss on health across the life span.
机译：背景。肥胖与老年人口中的死亡风险之间存在弱关系，但是，年龄对肥胖与发病率之间关系的影响尚不清楚。这项研究的目的是确定年龄对肥胖与心血管疾病，2型糖尿病，血脂异常和高血压之间关系的影响。方法。使用了第三次全国健康和营养检查调查（1988-1994）的数据。将个体分为特定年龄（年轻人：18-40岁;中层：40-65岁;年龄：65-75岁;非常年龄：≥75岁）和体重指数（BMI; 18.5-24.9，> 25-29.9，≥ 30kg / m2）类别。心血管疾病，2型糖尿病，血脂异常和高血压通过测量的代谢危险因素，医生诊断或药物使用进行分类。结果。年龄改变了BMI与心血管疾病（Age×BMI相互作用，p = .049），血脂异常（Age×BMI相互作用，男性p = .035，女性p <.001）和高血压（Age×女性的BMI相互作用，p = .023），而男性则没有（p = .167）。但是，年龄并未改变BMI与2型糖尿病之间的关系（年龄×BMI相互作用，p = .177）。 BMI与年轻人和中年人心血管疾病，血脂异常，2型糖尿病和高血压的相对危险性增加密切相关，但是，BMI与这些代谢状况之间的关系随着年龄的增长而大大减弱。结论。与中老年人相比，年轻和中年人群中的肥胖与普遍代谢状况之间的联系更紧密。需要进行纵向研究，以验证这些发现并确认减肥对整个生命周期健康的益处。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号