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首页> 外文期刊>The journals of gerontology.Series A. Biological sciences and medical sciences >Trajectories of gait speed predict mortality in well-functioning older adults: the Health, Aging and Body Composition study.
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Trajectories of gait speed predict mortality in well-functioning older adults: the Health, Aging and Body Composition study.

机译：步态速度轨迹可预测功能良好的老年人的死亡率：健康，衰老和身体成分研究。

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Although gait speed slows with age, the rate of slowing varies greatly. To date, little is known about the trajectories of gait speed, their correlates, and their risk for mortality in older adults.Gait speed during a 20-m walk was measured for a period of 8 years in initially well-functioning men and women aged 70-79 years participating in the Health, Aging and Body Composition study. We described the trajectories of gait speed and examined their correlates using a group-based mixture model. Also risk associated with different gait speed trajectories on all-cause mortality was estimated using a Cox-proportional hazard model.Of 2,364 participants (mean age, 73.5 ± 2.9 years; 52% women), we identified three gait speed trajectories: slow (n = 637), moderate (n = 1,209), and fast decline (n = 518). Those with fast decline slowed 0.030 m/s per year or 2.4% per year from baseline to the last follow-up visit. Women, blacks, and participants who were obese, had limited knee extensor strength, and had low physical activity were more likely to have fast decline than their counterparts. Participants with fast decline in gait speed had a 90% greater risk of mortality than those with slow decline.Despite being well-functioning at baseline, a quarter of older adults experienced fast decline in gait speed, which was associated with an increased risk of mortality.
机译：尽管步态速度随着年龄增长而减慢，但减慢的速度变化很大。迄今为止，关于步态速度的轨迹，其相关性以及对老年人的死亡风险知之甚少。在最初运行良好的男性和女性中，在20m的步行过程中步态速度进行了8年的测量。 70-79岁参加了健康，衰老和身体成分研究。我们描述了步态速度的轨迹，并使用基于组的混合模型检查了它们的相关性。还使用Cox比例风险模型估算了与不同步态速度轨迹引起的全因死亡率相关的风险。在2,364名参与者（平均年龄，73.5±2.9岁; 52％的女性）中，我们确定了三种步态速度轨迹：慢（n = 637），中等（n = 1,209）和快速下降（n = 518）。从基线到上次随访，那些快速下降的患者每年减慢0.030 m / s或每年2.4％。肥胖的女性，黑人和参与者，膝盖伸肌力量有限，体力活动较弱的人比同龄人更容易快速下降。步态快速下降的参与者的死亡风险比慢速下降的参与者高90％。尽管基线正常，但四分之一的老年人步态速度快速下降，这与死亡风险增加相关。

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