...
【24h】

Biorepair mechanisms and longevity.

机译:生物修复机制和长寿。

获取原文
获取原文并翻译 | 示例
           

摘要

The purpose of the study was to find out whether a link could be established between hypothetical biological repair mechanisms, their decay, and longevity. Human biological functions (biomarkers) can be classified accordingly as their generally linear age-related decline starts at birth or in adulthood ( approximately 1% per annum), or occurs at a rate of less than approximately 0.5% per annum Sums of exponentially declining functions representing the decline of repair mechanisms are fitted to the averages of each of the above groups. The time constants of the mechanisms are lowest for those ceasing normal function at the age of approximately 35-40 years, i.e., approximately at twice the maximal age at which puberty is reached. An extrapolation of the overall loss of the mechanisms, postulated to account for the declining biomarkers, is, at present, such as to reach zero in the twelfth decade of life.
机译:该研究的目的是找出是否可以在假设的生物修复机制,它们的衰变和寿命之间建立联系。可以将人类生物学功能(生物标记物)相应地归类为:它们通常与年龄相关的线性下降始于出生或成年(每年约1%),或者发生率每年低于约0.5%。代表修复机制下降的数据适用于上述每个组的平均值。对于那些在大约35-40岁时停止正常功能的人来说,该机制的时间常数最低,即大约在达到青春期的最大年龄的两倍。目前推测该机制的总体损失据推测是生物标志物下降的原因,例如在生命的第十二个十年达到零。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号