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首页> 外文期刊>The Journal of rheumatology >Comparison of the 2010 American College of Rheumatology/European League against Rheumatism and the 1987 American Rheumatism Association classification criteria for rheumatoid arthritis in an early arthritis cohort in New Zealand
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Comparison of the 2010 American College of Rheumatology/European League against Rheumatism and the 1987 American Rheumatism Association classification criteria for rheumatoid arthritis in an early arthritis cohort in New Zealand

机译:比较2010年美国风湿病学院/欧洲抗风湿病联盟与1987年美国风湿病协会在新西兰早期关节炎队列中对类风湿关节炎的分类标准

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Objective. To compare the performance of the 2010 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) criteria with the 1987 American Rheumatism Association (ARA) criteria for rheumatoid arthritis (RA) in an early arthritis cohort. Methods. The study included 79 patients with early arthritis (symptoms < 12 months) and a minimum of 1 year of followup between January 2004 and August 2010. Case notes were reviewed to determine which criteria were fulfilled at initial, 3-month, 1-year, and 2-year visits. Requirements for disease-modifying antirheumatic drug (DMARD) therapy and presence of joint erosions were compared at 2 years. Results. At the initial visit, twice as many patients fulfilled the 2010 criteria (67%) compared with the 1987 criteria (34%; p < 0.001). Forty-four percent of patients who fulfilled only the 2010 cri - teria at the initial visit went on to fulfill both 1987 and 2010 criteria at 3 months (p < 0.001). Eight patients did not meet the 1987 RA criteria solely because of short symptom duration. All 17/79 patients who developed joint erosions went on to eventually fulfill both criteria. Of those patients who fulfilled only the 2010 criteria at baseline, 25/27 (93%) ultimately received DMARD therapy compared with 24/26 (92%) of those fulfilling both 1987 and 2010 criteria. Conclusion. The 2010 ACR/EULAR RA criteria allowed earlier RA classification compared to the 1987 ARA criteria, although both criteria were equivalent in predicting joint erosions and sub - sequent need for DMARD (Australian New Zealand Clinical Trials Registry ANZCTR 12608000292370). The Journal of Rheumatology
机译:目的。为了比较2010年美国风湿病学院/欧洲风湿病联盟(ACR / EULAR)标准与1987年美国风湿病协会(ARA)对类风湿关节炎(RA)的标准在早期关节炎队列中的表现。方法。该研究纳入了79例早期关节炎(症状<12个月)的患者,在2004年1月至2010年8月之间进行了至少1年的随访。对病例记录进行了审查,以确定在最初,3个月,1年,和2年的访问。在2年时比较了改变疾病的抗风湿药(DMARD)治疗的要求和关节糜烂的存在。结果。在初次就诊时,符合1987年标准(34%; p <0.001)的患者达到2010年标准的两倍(67%)。初次访视时仅符合2010年标准的患者中有44%在3个月时继续符合1987年和2010年的标准(p <0.001)。仅由于症状持续时间短,八名患者不符合1987 RA标准。所有17/79例发生关节糜烂的患者均继续符合这两个标准。在基线时仅符合2010年标准的患者中,最终接受DMARD治疗的患者为25/27(93%),而同时符合1987年和2010年标准的患者为24/26(92%)。结论。与1987年的ARA标准相比,2010年的ACR / EULAR RA标准允许更早的RA分类,尽管这两个标准在预测关节糜烂和随后对DMARD的需求方面是等效的(澳大利亚新西兰临床试验注册中心ANZCTR 12608000292370)。风湿病学杂志

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