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首页> 外文期刊>The Journal of rheumatology >American college of rheumatology criteria at inception, and accrual over 5 years in the slicc inception cohort
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American college of rheumatology criteria at inception, and accrual over 5 years in the slicc inception cohort

机译：美国风湿病学院成立之初的标准，并在slicc成立队列中累积5年以上

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Objective: To determine the frequency of each American College of Rheumatology (ACR) criterion met at time of enrollment, and the increase in each of the criteria over 5 years. Methods: In 2000 the Systemic Lupus International Collaborating Clinics (SLICC) recruited an international inception cohort of patients with systemic lupus erythematosus (SLE;≥4 ACR criteria) who were followed at yearly intervals according to a standard protocol. Descriptive statistics were used to assess the total and cumulative number of ACR criteria met at each visit. Regression models were done to compare the increase of individual and cumulative criteria as a function of race/ethnicity group, and sex.Results: In all, 768 patients have been followed for a minimum of 5 years. Overall, 59.1% of the patients had an increase in the number of ACR criteria they met over the 5-year period. The mean number of ACR criteria met at enrollment was 5.04 ± 1.13 and at year 5 was 6.03 ± 1.42. At enrollment, nonwhite patients had a higher number of ACR criteria (5.19 ± 1.23) than white patients. The total number of criteria increased in both white and nonwhite ethnicities, but increased more among whites. Males had a slightly lower number of criteria at enrollment compared to females and males accrued fewer criteria at 5 years. Conclusion: In this international inception cohort of SLE patients with at least 4 ACR criteria at entry, there was an accumulation of ACR criteria over the following 5 years. The distribution of criteria both at inception and over 5 years is affected by sex and ethnicity.
机译：目的：确定入选时满足美国风湿病学院（ACR）各项标准的频率，以及每种标准在5年内的增长情况。方法：2000年，系统性红斑狼疮国际合作诊所（SLICC）招募了国际性的系统性红斑狼疮患者（SLE;≥4ACR标准）患者，按照标准方案每年进行随访。描述性统计数据用于评估每次访问时符合的ACR标准总数和总数。进行回归模型以比较个体和累积标准随种族/族裔群体和性别的增加。结果：总共对768名患者进行了至少5年的随访。总体而言，在5年中，他们符合的ACR标准数量增加了59.1％。入学时符合ACR标准的平均数为5.04±1.13，第5年为6.03±1.42。在入组时，非白人患者的ACR标准数高于白人患者（5.19±1.23）。白人和非白人族裔的标准总数都有所增加，但在白人中则有所增加。与女性相比，男性的入学标准数量略低，而男性在5年时的入学标准较少。结论：在国际入组的SLE患者入组时至少有4条ACR标准，在随后的5年中积累了ACR标准。从一开始和超过5年的标准分布受性别和种族的影响。

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