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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >Effects of acute thyroxin depletion on hearing in humans.
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Effects of acute thyroxin depletion on hearing in humans.

机译：急性甲状腺素耗竭对人类听力的影响。

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OBJECTIVE: To study the physiologic effect of acute thyroid hormone depletion on hearing and the function of outer hair cells. DESIGN: Audiologic and otoacoustic emission testing of subjects undergoing total thyroidectomy before surgery and up to 6 weeks after surgery. Magnitude of thyroxin depletion monitored by serum thyroid-stimulating hormone levels. SETTING: Hearing research laboratory at a state university. SUBJECTS: Ten patients undergoing total thyroidectomy. MAIN OUTCOME MEASURES: Detection of hearing loss on audiogram and decrease or disappearance of otoacoustic emissions as a result of acute thyroxin depletion. RESULTS: No significant changes in the audiogram and otoacoustic emission configurations were detected, although thyroid-stimulating hormone levels became elevated after total thyroidectomy. CONCLUSION: Although thyroid hormone is thought to play a role in the physiology of hearing in humans, no deleterious effects on hearing can be identified up to 6 weeks after thyroxin depletion.
机译：目的：研究急性甲状腺激素耗竭对听力和外毛细胞功能的生理影响。设计：对术前和术后6周进行全甲状腺切除术的受试者进行听觉和耳声发射测试。通过血清促甲状腺激素水平监测甲状腺素耗竭量。地点：州立大学的听力研究实验室。受试者：十名接受全甲状腺切除术的患者。主要观察指标：检测由于急性甲状腺素消耗而导致听力图听力下降以及耳声发射减少或消失的情况。结果：尽管全甲状腺切除术后甲状腺刺激激素水平升高，但听力图和耳声发射结构未见明显变化。结论：尽管甲状腺激素被认为在人类的听觉生理中起着作用，但在甲状腺素耗尽后6周内仍未发现对听觉的有害影响。

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