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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >Efficacy of laryngeal botulinum toxin injection: Comparison of two techniques.
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Efficacy of laryngeal botulinum toxin injection: Comparison of two techniques.

机译：喉肉毒杆菌毒素注射的功效：两种技术的比较。

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摘要

OBJECTIVES/HYPOTHESIS: It is hypothesized that there is no difference in the effectiveness of botulinum toxin (BTX) injection between electromyography (EMG)-guided and non-EMG guided "point-touch" techniques in the treatment of adductor spasmodic dysphonia. STUDY DESIGN: Retrospective chart review. METHODS: Patients selected for evaluation underwent sequential treatment by one or both of the senior authors using two different injection techniques with similar BTX dilution and preparation. Data gathered included dose injected, injection effect, and presence and duration of breathiness and dysphagia after injection. Statistical analysis was performed used a generalized estimating equations model. RESULTS: A total of 417 injections in 64 patients were analyzed. There was no difference in the rate of successful injections between the EMG-guidance group and the non-EMG guidance group (94.4% and 93.2%, respectively; P = .7). CONCLUSIONS: This unique study demonstrates that efficacy of BTX does not necessarily depend on the method of injection used. In experienced hands, excellent clinical results can be achieved with either EMG-guided or non-EMG guided injection techniques.
机译：目的/假设：假设肌电图（EMG）指导和非EMG指导的“点触”技术在治疗内收肌痉挛性肌张力障碍中注射肉毒杆菌毒素（BTX）的有效性没有差异。研究设计：回顾性图表审查。方法：由一位或两位资深作者采用两种相似的BTX稀释和制备方法，采用两种不同的注射技术，对被选择进行评估的患者进行顺序治疗。收集的数据包括注射剂量，注射效果以及注射后呼吸和吞咽困难的存在和持续时间。使用广义估计方程模型进行统计分析。结果：共分析了64例患者的417次注射。 EMG指导组和非EMG指导组之间的成功注射率没有差异（分别为94.4％和93.2％; P = 0.7）。结论：这项独特的研究表明BTX的疗效并不一定取决于所用的注射方法。在经验丰富的手中，通过EMG引导或非EMG引导的注射技术均可获得出色的临床效果。

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