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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >A cost-effectiveness analysis of positron emission tomography-computed tomography surveillance versus up-front neck dissection for management of the neck for N2 disease after chemoradiotherapy.
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A cost-effectiveness analysis of positron emission tomography-computed tomography surveillance versus up-front neck dissection for management of the neck for N2 disease after chemoradiotherapy.

机译：对正电子放射断层扫描，计算机断层扫描监视与前颈清扫术进行放化疗后N2疾病进行颈部管理的成本效益分析。

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OBJECTIVES/HYPOTHESIS: To study the cost effectiveness of positron emission tomography-computerized tomography (PET-CT) scanning in the management of the neck after chemoradiotherapy (CRT). STUDY DESIGN: Cost effectiveness and decision analysis model. METHODS: A cost-effectiveness analysis comparing up-front neck dissection to serial PET-CT imaging in a hypothetical clinical scenario of debate. A patient with an oropharygeal cancer with pretreatment N2 disease having a complete response was considered. Standardized costs were obtained using national databases. A literature review in PubMed was performed to obtain information on incidence, probabilities, and range for various clinical events in the algorithm. RESULTS: PET-CT strategy costs an average of Dollars 14,492 per patient. Neck dissection had a 0.6% greater efficacy in controlling neck disease with a Dollars 22,433 incremental cost. CONCLUSIONS: Our results strongly support the use of PET-CT imaging as the more cost-effective strategy for surveillance of neck after completion of definitive CRT compared to up-front neck dissection.
机译：目的/假设：为了研究正电子放射断层扫描计算机断层扫描（PET-CT）扫描在放化疗后（CRT）颈部管理中的成本效益。研究设计：成本效益和决策分析模型。方法：成本效益分析比较在一个假设的临床情况下前颈淋巴结清扫与连续PET-CT成像。考虑患有具有完全反应的N2预处理疾病的口咽癌患者。标准化费用是使用国家数据库获得的。在PubMed中进行了文献综述，以获取有关算法中各种临床事件的发生率，概率和范围的信息。结果：PET-CT策略平均每位患者花费14,492美元。颈部清扫术在控制颈部疾病方面的功效提高了0.6％，增加了22,433美元的费用。结论：我们的研究结果强烈支持使用PET-CT成像作为与最终前路颈清扫术相比完成确定性CRT后更具成本效益的颈部监测策略。

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