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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >Swallowing pressure and pressure profiles in young healthy adults
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Swallowing pressure and pressure profiles in young healthy adults

机译：年轻健康成年人的吞咽压力和压力曲线

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摘要

Objectives/Hypothesis To measure the swallowing pressure (SP) of normal subjects using a 2.64-mm-diameter high-resolution manometry (HRM) catheter with 36 circumferential sensors. Study Design Repeated measures with subjects serving as controls. Methods Thirty healthy subjects swallowed water at different temperatures and volumes to examine the maximum SP at the velopharynx, meso-hypopharynx, upper esophageal sphincter (UES), and cervical esophagus, and the duration of lowered pressure at the UES. Results The maximum SP at any location was unaffected by the volume of water, whereas the maximum SP at the UES and cervical esophagus was affected by the temperature. The duration of lowered SP at the UES was significantly prolonged with 10 versus 2 mL of cold water. The pressure curve in males had two peaks (at the velopharynx and UES), whereas that of females had a single peak at the UES. Conclusions Our data obtained with 2.64-mm HRM demonstrated that as the bolus volume is increased, the duration of lowered SP at the UES is prolonged. The higher maximum SP at the velopharynx in males versus females suggests that there may be a gender difference in pressure at the velopharynx that has not been described previously. This implies that it is necessary to take gender differences into consideration when evaluating the etiology of swallowing dysfunction by examining the SP and SP curve. Moreover, the thinner catheter is less invasive and may contribute to obtaining more physiological measurements.
机译：目的/假设使用具有36个圆周传感器的直径为2.64毫米的高分辨率测压（HRM）导管来测量正常受试者的吞咽压力（SP）。研究设计以受试者为对照的重复测量。方法30名健康受试者吞咽不同温度和体积的水，以检查口咽部，中咽部，上食道括约肌（UES）和宫颈食道的最大SP，以及UES的降压持续时间。结果任何位置的最大SP不受水量的影响，而UES和宫颈食道的最大SP受温度的影响。与10 mL和2 mL冷水相比，UES处SP降低的持续时间显着延长。雄性的压力曲线有两个峰值（在口咽处和UES处），而雌性的压力曲线在UES处有一个峰值。结论我们使用2.64毫米HRM获得的数据表明，随着推注量的增加，UES降低SP的持续时间会延长。男性与女性在口咽处的最高SP值较高，这表明口咽处的压力可能存在性别差异，这一点以前没有描述过。这意味着在通过检查SP和SP曲线评估吞咽功能障碍的病因时，有必要考虑性别差异。此外，较细的导管侵入性较小，并且可能有助于获得更多的生理测量值。

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