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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >Transmucosal fine-needle aspiration diagnosis of intraoral and intrapharyngeal lesions.
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Transmucosal fine-needle aspiration diagnosis of intraoral and intrapharyngeal lesions.

机译：经粘膜细针穿刺术诊断口腔内和咽内病变。

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摘要

OBJECTIVES: The effectiveness of fine-needle aspiration biopsy (FNAB) for the diagnosis of neck, thyroid, and salivary gland masses is well documented. Very few reports explore the potential of an intraoral FNAB approach for the diagnosis of submucosal lesions. We describe our technique and present case examples of pertinent differential diagnostic entities. We recommend an expanded role for FNAB of the oral cavity and oropharynx. STUDY DESIGN: Retrospective review. METHODS: A uniform technique was employed for transmucosal FNAB of 76 patients with intraoral masses. In applicable cases, cytology results were compared with traditional biopsy methods and permanent histopathologic specimens for accuracy. RESULTS: Our experience demonstrates the high sensitivity (93%) and specificity (86%) of intraoral FNAB when compared with biopsy by conventional means. FNAB provides distinct advantages for the cytologic diagnosis of submucosal lesions, which may be difficult to reach and adequately sample through conventional biopsy. FNAB of the tonsil and tonsillar fossa provides a safe and effective means of diagnosing both lymphoma and squamous cell cancer. Transmucosal FNAB via the mouth led to rapid diagnosis of a number of benign and malignant lesions. Applying this uniform FNAB technique, we had no significant complications. CONCLUSION: We recommend transmucosal FNAB as an effective means for highly accurate diagnosis of submucosal lesions of the oral cavity and oropharynx. CLINICAL RELEVANCE: Traditional biopsy techniques in the oral cavity may require anesthesia and may have diagnostic difficulties, particularly for submucosal lesions. Transmucosal FNAB overcomes these shortcomings by providing a minimally invasive means to rapid diagnosis of intraoral lesions.
机译：目的：细针穿刺活检（FNAB）在诊断颈部，甲状腺和唾液腺肿块中的有效性已得到充分证明。很少有报道探讨口腔内FNAB方法在粘膜下病变诊断中的潜力。我们描述了我们的技术，并介绍了相关鉴别诊断实体的案例。我们建议扩大口腔和口咽FNAB的作用。研究设计：回顾性审查。方法：采用统一技术对76例口腔内包块患者经粘膜FNAB进行检查。在适用的情况下，将细胞学结果与传统的活检方法和永久性组织病理学样本进行比较，以确保准确性。结果：我们的经验表明，与常规方式的活检相比，口腔内FNAB的敏感性高（93％），特异性高（86％）。 FNAB为粘膜下病变的细胞学诊断提供了独特的优势，而传统的活检可能很难达到这一要求，并且需要进行充分的采样。扁桃体和扁桃体窝的FNAB为淋巴瘤和鳞状细胞癌的诊断提供了一种安全有效的方法。经口粘膜穿刺FNAB可快速诊断许多良性和恶性病变。应用这种统一的FNAB技术，我们没有明显的并发症。结论：我们建议采用粘膜粘膜NAB作为高精度诊断口腔和口咽粘膜下病变的有效方法。临床意义：传统的口腔活检技术可能需要麻醉，并且可能存在诊断困难，尤其是对于粘膜下病变。透粘膜FNAB通过提供一种微创手段快速诊断口腔内病变来克服这些缺点。

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