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Short-term objective and long-term subjective results of laser-assisted uvulopalatoplasty for obstructive sleep apnea.

机译:激光辅助葡萄膜成形术治疗阻塞性睡眠呼吸暂停的短期客观和长期主观结果。

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OBJECTIVES: To determine the short-term and long-term effects of laser-assisted uvulopalatoplasty (LAUP) on symptoms and polysomnographic measures in patients with obstructive sleep apnea syndrome (OSAS). STUDY DESIGN: Prospective assessment of outcomes after LAUP in patients with OSAS. METHODS: Fifty-nine patients with OSAS underwent LAUP, and 36 completed postoperative sleep studies. Questionnaires ranking snoring and apneic symptoms were completed by the patient and bed partner before LAUP, 6 to 12 weeks after LAUP, and in the long term (> 2 years). RESULTS: The apnea index decreased from 14.4 to 5.8 (P = .0012), respiratory disturbance index (RDI) decreased from 28.1 to 7.9 (P = .0046), and the mean lowest oxyhemoglobin saturation increased from 80.6% to 84.0% (P = .055). The RDI was reduced to 10 or less in 44.4% of patients. Subjective questionnaires showed statistically significant improvements in snoring, morning fatigue, morning headaches, daytime somnolence, and daytime psychometric measures. The symptomatic improvement persisted in the long term. CONCLUSIONS: LAUP is an effective method for the management of OSAS. We have demonstrated short-term improvement in polysomnographic measures and short-term and long-term improvement in subjective measures.
机译:目的:确定激光辅助下睑成形术(LAUP)对阻塞性睡眠呼吸暂停综合症(OSAS)患者的症状和多导睡眠图测量的短期和长期影响。研究设计:对OSAS患者进行LAUP后的预后评估。方法:对59例OSAS患者进行了LAUP,其中36例完成了术后睡眠研究。患者和卧床伴侣在LAUP前,LAUP后6至12周以及长期(> 2年)内完成打ranking和呼吸暂停症状的问卷调查。结果:呼吸暂停指数从14.4下降至5.8(P = .0012),呼吸障碍指数(RDI)从28.1下降至7.9(P = .0046),平均最低氧合血红蛋白饱和度从80.6%上升至84.0%(P = .055)。 44.4%的患者的RDI降至10或更低。主观调查问卷显示,打,早晨疲劳,早晨头痛,白天嗜睡和白天心理测验有统计学上的显着改善。症状改善长期持续。结论:LAUP是管理OSAS的有效方法。我们已经证明了多导睡眠图测量的短期改善以及主观测量的短期和长期改善。

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