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Subglottic laryngeal paraganglioma.

机译:声门下喉旁神经节瘤。

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摘要

OBJECTIVES: To review the clinical and pathological picture of laryngeal paragangliomas and compare laryngeal paragangliomas with the three other types of laryngeal neuroendocrine neoplasms. STUDY DESIGN: The study presents a case review of a patient with a subglottic laryngeal paraganglioma treated at our institution, with a literature review of the laryngeal neuroendocrine neoplasms. Included is a review of all four neuroendocrine neoplasms, taking a close look at a comparison between laryngeal paragangliomas and atypical carcinoids tumors. All cases of subglottic laryngeal paragangliomas reported in the literature were also compiled and tabulated. METHODS: The patient's record was reviewed for age, symptomatology, workup, and surgical procedures performed. RESULTS: The patient was disease free 36 months after undergoing a tracheostomy for airway control, followed by a cricoid split for complete excision of the tumor. CONCLUSIONS: It is important to differentiate among the four laryngeal neuroendocrine neoplasms, especially between atypical carcinoids and paragangliomas. Each tumor requires different treatments, with the former requiring a more aggressive approach. Paragangliomas must be completely excised to prevent their recurrence, and this approach should be considered a curative treatment. In addition, the immunohistochemical battery is of paramount importance in obtaining the correct pathological diagnosis.
机译:目的:回顾喉旁神经节瘤的临床和病理学特征,并将喉旁神经节瘤与其他三种类型的喉神经内分泌肿瘤进行比较。研究设计:本研究对在我院接受治疗的声门下喉旁神经节瘤患者进行病例回顾,并对喉神经内分泌肿瘤进行文献综述。其中包括对所有四个神经内分泌肿瘤的综述,仔细观察了喉旁神经节瘤与非典型类癌肿瘤之间的比较。文献中报道的所有声门下喉旁神经节瘤病例均已汇总并制成表格。方法:对患者的病历,年龄,症状,检查和手术方法进行了回顾。结果:该患者接受气管切开术进行气道控制36个月后无病,随后进行了环状切开术以完全切除肿瘤。结论:重要的是要区分四种喉神经内分泌肿瘤,特别是非典型类癌和神经节旁瘤。每个肿瘤需要不同的治疗方法,前者需要更积极的治疗方法。副神经节瘤必须完全切除以防止其复发,这种方法应被视为治疗方法。此外,免疫组化电池对于获得正确的病理诊断至关重要。

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