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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >Outpatient intravenous antibiotics for chronic rhinosinusitis.
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Outpatient intravenous antibiotics for chronic rhinosinusitis.

机译：门诊静脉注射抗生素用于慢性鼻-鼻窦炎。

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OBJECTIVE/HYPOTHESIS Peripherally inserted central catheter (PICC) lines have greatly facilitated the use of intravenous antibiotics in outpatient medical practice. Otolaryngologic applications for home intravenous therapy through PICC lines have not been well characterized to date. The purpose of the study is to describe indications and complications related to outpatient intravenous antibiotic therapy in patients with chronic rhinosinusitis.STUDY DESIGN Retrospective cohort study.METHODS Chart review of patients with chronic rhinosinusitis who were treated at an academic rhinology practice with outpatient intravenous antibiotics over a 3-year period.RESULTS Fourteen patients receiving, in all, 16 courses of intravenous antibiotic therapy through PICC line were identified. The average patient age was 51 years (age range, 36-74 y). The primary indication for intravenous antibiotic use was the treatment of resistant pathogens (50%). The most common organisms treated were, and. Other indications included gastrointestinal intolerance of oral antibiotics and extranasal complications of sinusitis. Eighty-eight percent of patients (14 of 16) were able to complete the entire prescribed course of therapy. Three (19%) catheter-related complications occurred, including thrombophlebitis and deep venous thrombosis. All three complications required removal of the PICC line; one of these patients underwent successful reinsertion of a second catheter and completion of treatment.CONCLUSIONS Peripherally inserted central catheter line delivery of home intravenous antibiotics can be a well-tolerated adjunct to surgery in the outpatient treatment of chronic rhinosinusitis. Resistant infections, intolerance to oral antimicrobials, and extranasal complications of sinusitis are indications for PICC line therapy. Catheter-related complications can be significant and must be considered in patient selection.
机译：目的/假说外围插入的中心导管（PICC）线极大地方便了门诊医疗实践中静脉注射抗生素的使用。迄今为止，通过PICC管线进行家庭静脉治疗的耳鼻喉科应用尚未得到很好的表征。这项研究的目的是描述与慢性鼻-鼻窦炎患者门诊静脉抗生素治疗有关的适应症和并发症。研究设计回顾性队列研究方法图表回顾性回顾了在学术流变实践中接受过门诊静脉内抗生素治疗的慢性鼻-鼻窦炎患者结果共有14例患者通过PICC线接受了16个疗程的静脉抗生素治疗。患者平均年龄为51岁（年龄范围：36-74岁）。静脉使用抗生素的主要指征是治疗耐药病原体（50％）。被治疗的最常见的生物是和。其他适应症包括口服抗生素的胃肠道不耐受和鼻窦炎的鼻外并发症。 88％的患者（16名患者中的14名）能够完成整个规定的治疗过程。发生了三项（19％）与导管相关的并发症，包括血栓性静脉炎和深静脉血栓形成。所有这三种并发症都需要删除PICC生产线。这些患者中的一位成功地重新插入了第二根导管并完成了治疗。结论结论：在家庭门诊治疗慢性鼻-鼻窦炎时，外周静脉插入中心静脉导管输送家庭静脉内抗生素可能是手术的良好耐受性。耐药感染，对口服抗菌药物的耐受性以及鼻窦炎的鼻外并发症是PICC线治疗的指征。与导管相关的并发症可能很严重，在选择患者时必须予以考虑。

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