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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >Paradoxical spread of renal cell carcinoma to the head and neck.
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Paradoxical spread of renal cell carcinoma to the head and neck.

机译：肾细胞癌到头部和颈部的反常扩散。

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摘要

OBJECTIVES: To present cases of renal cell carcinoma presenting with only head and neck metastases, to review theories of physiology and anatomy describing this phenomenon, and to discuss the role of the otolaryngologist in the treatment of these lesions. STUDY DESIGN: Retrospective review of the records of three patients who presented with renal cell carcinoma with head and neck metastases over the 3-year period from 1992 to 1995. METHODS: Retrospective review of the records of three patients who presented with renal cell carcinoma with head and neck metastases. In addition, English-language literature was reviewed with special focus on the anatomic and physiologic pathways possible to allow for such a phenomenon. CONCLUSIONS: Renal cell carcinoma has an occasional presentation as a head and neck mass without evidence of disease elsewhere. Various routes of spread have been postulated. Batson's venous plexus, as postulated by Nahum and Bailey, is an anatomic route through which emboli could navigate to the head and neck and avoid pulmonary vascular filtration. Interactions on the cellular level may also be responsible for the seemingly paradoxical spread. We recommend local excision of head and neck metastases of renal cell carcinoma without sacrifice of vital structures as a sound treatment regimen.
机译：目的：介绍仅头部和颈部转移的肾细胞癌病例，回顾描述该现象的生理学和解剖学理论，并讨论耳鼻喉科医师在这些病变的治疗中的作用。研究设计：回顾性回顾了1992年至1995年这3年间3例头颈部转移性肾细胞癌患者的记录。方法：回顾性分析了3例合并肾细胞癌的肾细胞癌患者的记录。头部和颈部转移。此外，对英语文献进行了审查，特别侧重于可能允许这种现象的解剖和生理途径。结论：肾细胞癌偶有头颈部肿块，无其他部位疾病迹象。假定了各种传播途径。根据Nahum和Bailey的假设，Batson的静脉丛是一种解剖学途径，栓子可以通过该途径到达头部和颈部，并避免肺血管滤过。在细胞水平上的相互作用也可能导致看似矛盾的扩散。我们建议局部切除肾细胞癌的头部和颈部转移灶，而不牺牲重要结构，以此作为合理的治疗方案。

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