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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >Comparison of biomechanical properties of alloderm and enduragen as static facial sling biomaterials.
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Comparison of biomechanical properties of alloderm and enduragen as static facial sling biomaterials.

机译：异体皮和耐力原作为静态面巾吊带生物材料的生物力学性能比较。

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BACKGROUND: Static slings are one of the most commonly used surgical rehabilitation methods in the management of chronic facial paralysis. Acellular human cadaveric dermis (Alloderm; Life Cell Corp., Branchburg, NJ) is used for this purpose; however, it has variable stretching properties that may necessitate additional "tuning-up" procedure(s). Acellular porcine dermis (Enduragen; Tissue Sciences Laboratories, plc., Aldershot, U.K.) was recently introduced as a biologic implant and it is compositionally similar to Alloderm. However, no data currently exist regarding its biomechanical properties and potential use as an alternative implant to Alloderm in static facial sling procedures. OBJECTIVE: The objective of this study was to compare the biomechanical properties of Alloderm and Enduragen for static facial sling procedures in the management of the paralytic face. STUDY DESIGN: This study consisted of an in vitro prospective study in an academic medical research setting. METHODS: Same size and thickness Alloderm and Enduragen samples were tested with MTS 858 Bionix materials test system for load-to-failure, displacement under increasing and constant stress, and stiffness. RESULTS: Enduragen showed significantly less elongation under increasing stress and at the beginning of constant stress. Load-to-failure and stiffness were significantly higher in Alloderm; however, both biomaterials have adequate stiffness and load-to-failure for a static facial sling procedure. CONCLUSIONS: Enduragen may serve as another potential static facial sling material, because it stretches significantly less than Alloderm under stress. Clinical experience is needed with Enduragen to determine its potential use as a static facial sling material.
机译：背景：静态吊索是慢性面瘫治疗中最常用的外科康复方法之一。无细胞的人体尸体真皮（Alloderm; Life Cell Corp.，Branchburg，NJ）用于此目的。但是，它具有可变的拉伸特性，可能需要其他“调整”过程。最近引入了无细胞猪真皮（Enduragen;组织科学实验室，PLC，英国Aldershot）作为生物植入物，其成分类似于异位真皮。但是，目前尚无有关其生物力学性能和在静态面部悬带手术中作为Alloderm替代植入物的潜在用途的数据。目的：本研究的目的是比较Alloderm和Enduragen在处理麻痹性面部的静态面部悬带手术中的生物力学特性。研究设计：该研究包括在学术医学研究环境中进行的体外前瞻性研究。方法：使用MTS 858 Bionix材料测试系统测试了相同大小和厚度的Alloderm和Enduragen样品的载荷-破坏，在不断增加的应力和恒定应力下的位移以及刚度。结果：Enduragen在应力增加和恒定应力开始时的伸长率明显降低。 Alloderm的破坏载荷和刚度明显更高;但是，两种生物材料都具有足够的刚度和承受静态面部悬带手术的失败载荷。结论：Enduragen可以用作另一种潜在的静态面部悬带材料，因为它在压力下的拉伸力明显小于Alloderm。需要Enduragen的临床经验来确定其作为静态面部悬带材料的潜在用途。

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