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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >Tuberculous otitis media: a clinical and radiologic analysis of 52 patients.
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Tuberculous otitis media: a clinical and radiologic analysis of 52 patients.

机译：结核性中耳炎：52例患者的临床和影像学分析。

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OBJECTIVE: This retrospective study reports on the clinical and radiologic features and the treatment outcomes of patients with tuberculous otitis media (TOM). METHODS: We reviewed the medical records of 52 patients (53 ears) with TOM between 1993 and 2005 and analyzed temporal bone computed tomography scans of 23 patients. The diagnosis of TOM was made if a specimen of the middle ear revealed the presence of acid fast bacilli (AFB), grew Mycobacterium tuberculosis (M. Tb) on a culture, revealed characteristic histology, and/or was positive for polymerase chain reaction (PCR) for M. Tb. RESULTS: The highest incidence of the disease was observed among patients in their 30s. The main symptom was otorrhea, and the duration of symptoms was shorter than with nonspecific chronic otitis media. Most patients demonstrated a moderate to severe hearing loss. Five patients (9.6%) demonstrated a peripheral-type facial palsy. Temporal bone CT scans demonstrated relatively well-pneumatized mastoids and occupation by soft tissue of the entire tympanum and mastoid air cells. Six patients demonstrated bone destruction that involved the cortex of the mastoid bone. In most patients, antituberculous medication was effective treatment. The patients who underwent chemotherapy after surgery achieved more rapid healing of the ear and more frequent closure of the tympanic membrane than those who did not receive surgery. CONCLUSIONS: Clinicians should have a high index of suspicion and be aware of the clinical and radiologic characteristics of TOM.
机译：目的：这项回顾性研究报告了结核性中耳炎（TOM）患者的临床和影像学特征以及治疗结果。方法：我们回顾了1993年至2005年间52例TOM患者（53耳）的病历，并对23例患者的颞骨计算机断层扫描进行了分析。如果中耳标本显示存在耐酸杆菌（AFB），在培养物上生长了结核分枝杆菌（M. Tb），组织学特征明显和/或聚合酶链反应呈阳性（ PCR）。结果：在30多岁的患者中，该病的发病率最高。主要症状是耳漏，症状持续时间比非特异性慢性中耳炎短。大多数患者表现出中度至重度听力下降。五名患者（9.6％）表现出周围型面神经麻痹。颞骨CT扫描显示相对良好的乳突气肿，整个鼓膜和乳突气胞被软组织占据。六名患者表现出涉及乳突骨皮质的骨破坏。在大多数患者中，抗结核药物是有效的治疗方法。与未接受手术的患者相比，术后接受化学疗法的患者的耳朵愈合更快，鼓膜闭合的频率更高。结论：临床医师应高度怀疑，并应了解TOM的临床和影像学特征。

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