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New staging system for sinonasal inverted papilloma in the endoscopic era.

机译:内窥镜时代鼻窦倒置乳头状瘤的新分期系统。

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OBJECTIVES: Advanced endoscopic techniques have emerged as the preferred treatment modality for sinonasal inverted papilloma (IP); however, a staging system that provides prognostic information has not yet been developed. This study aims to develop a clinically relevant staging system for IP managed with the endoscopic approach as the primary surgical modality. DESIGN: A systematic review of the English-language literature (1985-2006) and a single institution's experience. METHODS: From the literature, 445 patients with IP treated by endoscopic resection were identified in 14 reports. Only patients with known IP sites and outcomes were included. RESULTS: Patients were categorized into three groups on the basis of recurrence rates (RR): group A (IP confined to the nasal cavity, ethmoid sinus, and medial maxillary sinus), 3.0% RR (n = 234); group B (IP with lateral maxillary sinus, sphenoid sinus, or frontal sinus involvement), 19.8% RR (n = 177); and group C (IP with extrasinus extension), 35.3% RR (n =34). Pearson's chi-square test showed statistically significant differences for all pair-wise comparisons between groups (P < .05). Mean follow-up was 39.8 months. CONCLUSIONS: This new staging system for IP provides information about prognosis (as operationally defined by RR) for IP managed by advanced endoscopic techniques. In contrast, other staging systems for IP reflect surgeon's judgment rather than outcomes data. This new classification for IP provides important objective data for preoperative planning and patient counseling.
机译:目的:先进的内窥镜技术已成为鼻窦倒置性乳头状瘤(IP)的首选治疗方式。但是,尚未开发出可提供预后信息的分期系统。这项研究的目的是开发一种临床相关的IP分期系统,以内镜作为主要手术方式进行管理。设计:对英语文献(1985-2006年)的系统评价和单个机构的经验。方法:从文献中,在14篇报告中确定了445例经内镜切除术治疗的IP患者。仅包括具有已知IP位点和结果的患者。结果:根据复发率(RR)将患者分为三组:A组(IP局限于鼻腔,筛窦和内侧上颌窦),3.0%RR(n = 234); B组(IP伴上颌窦外侧,蝶窦或额窦受累),RR 19.8%(n = 177); C组(腹膜外延伸的IP),RR为35.3%(n = 34)。皮尔逊卡方检验显示,各组之间所有成对比较的统计学差异显着(P <.05)。平均随访39.8个月。结论:这种新的IP分期系统提供了有关由先进内窥镜技术管理的IP预后的信息(如RR所定义)。相反,其他用于IP的分期系统则反映了外科医生的判断而不是结果数据。这种新的IP分类为术前计划和患者咨询提供了重要的客观数据。

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