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Artificial manipulation of voice in the human by an implanted stimulator.

机译:通过植入的刺激器对人的声音进行人工操纵。

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摘要

OBJECTIVES/HYPOTHESIS: Traditional approaches influencing voice quality (e.g., anatomical and chemical denervation for spasmodic dysphonia, surgical medialization for paralysis) have ignored the dynamic nature of the larynx. STUDY DESIGN: We report here the first attempt to manipulate voice using an implanted stimulator to systematically control vocal fold adduction. METHODS: Devices placed for aspiration in three subjects retaining speech after stroke, cerebral palsy, and multiple sclerosis were used to stimulate recurrent laryngeal nerves with 42 Hz, 52 to 200 microsecond pulses of incremental amplitudes during phonation with the tracheostomy tube occluded. Vocal fold adduction increased with stimulation strength (P < .05). Speech was analyzed with the Vox Metria program. RESULTS: We found highly significant differences for fundamental frequency (P < .007), jitter (P < .004), and shimmer (P < .005), between natural and stimulated voice (aah and eeh) when using higher charges. CONCLUSIONS: Dynamic vocal fold manipulation seems promising in terms of versatility lacking with static approaches to voice control.
机译:目标/假设:影响语音质量的传统方法(例如,痉挛性发音障碍的解剖和化学去神经支配,瘫痪的手术介导)忽略了喉部的动态特性。研究设计:我们在这里报告的第一次尝试使用植入的刺激器来系统地控制声带内收来操纵声音。方法:在三名中风,脑瘫和多发性硬化症后仍保留语音的受试者中,用于抽吸的装置被用来刺激喉管造口术,在发声时以42 Hz,52至200微秒的增量振幅刺激喉返神经。声带内收随刺激强度的增加而增加(P <.05)。使用Vox Metria程序分析了语音。结果:当使用较高的电荷时,我们发现自然声音和受激声音(aah和eeh)之间的基本频率(P <.007),抖动(P <.004)和微光(P <.005)的显着差异。结论:动态声带操纵在缺乏通用的语音控制静态方法方面似乎很有希望。

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