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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >Vestibular evoked myogenic potentials (VEMP) can detect asymptomatic saccular hydrops.
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Vestibular evoked myogenic potentials (VEMP) can detect asymptomatic saccular hydrops.

机译：前庭诱发的肌原性电位（VEMP）可以检测无症状的囊性积液。

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OBJECTIVE: The objective of this study was to explore the useful of vestibular evoked myogenic potential (VEMP) testing for detecting endolymphatic hydrops, especially in the second ear of patients with unilateral Meniere disease (MD). METHODS: This study was performed at a tertiary care academic medical center. Part I consisted of postmortem temporal bone specimens from the temporal bone collection of the Massachusetts Eye & Ear Infirmary; part II consisted of consecutive consenting adult patients (n = 82) with unilateral MD by American Academy of Otolaryngology-Head and Neck Surgery criteria case histories. Outcome measures consisted of VEMP thresholds in patients and histologic saccular endolymphatic hydrops in postmortem temporal bones. RESULTS: Saccular hydrops was observed in the asymptomatic ear in six of 17 (35%) of temporal bones from donors with unilateral MD. Clinic patients with unilateral MD showed elevated mean VEMP thresholds and altered VEMP tuning in their symptomatic ears and, to a lesser degree, in their asymptomatic ears. Specific VEMP frequency and tuning criteria were used to define a "Meniere-like" response. This "Meniere-like" response was seen in 27% of asymptomatic ears of our patients with unilateral MD. CONCLUSIONS: Bilateral involvement is seen in approximately one third of MD cases. Saccular hydrops appears to precede symptoms in bilateral MD. Changes in VEMP threshold and tuning appear to be sensitive to these structural changes in the saccule. If so, then VEMP may be useful as a detector of asymptomatic saccular hydrops and as a predictor of evolving bilateral MD.
机译：目的：本研究的目的是探讨前庭诱发肌原性电位（VEMP）检测在检测内淋巴积液方面的有用性，特别是在单侧美尼尔病（MD）患者的第二耳中。方法：本研究在三级医疗学术医学中心进行。第一部分包括马萨诸塞州眼耳医院颞骨采集的颞骨标本。第二部分由美国耳鼻咽喉科学-头颈外科标准病例史的连续同意成年患者（n = 82）单侧MD组成。结果测量包括患者的VEMP阈值和死后颞骨的组织学囊性内淋巴积液。结果：在单侧MD捐献者的17例颞骨中，有6例（35％）的无症状耳朵出现囊性积液。单侧MD的临床患者在症状性耳朵和无症状性耳朵中显示出较高的平均VEMP阈值并改变了VEMP调节。使用特定的VEMP频率和调整标准来定义“类似Meniere”的响应。在单侧MD患者的27％无症状耳朵中可以看到这种“ Meniere样”反应。结论：在大约三分之一的MD病例中发现有双边受累。囊性积液似乎先于双侧MD的症状。 VEMP阈值和调整的变化似乎对球囊中的这些结构变化敏感。如果是这样，那么VEMP可用作无症状囊性积液的检测器和双侧MD演变的预测指标。

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