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Endoscopic endonasal management of pseudotumor cerebri: is it effective?

机译:内窥镜鼻腔假瘤脑处理:有效吗?

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摘要

PURPOSE: To study the efficacy and safety of endoscopic endonasal optic nerve fenestration for the management of idiopathic intracranial hypertension (IIH). DESIGN: A prospective study at a tertiary care center. PATIENTS AND METHODS: All patients with a final diagnosis of IIH from July 2001 to March 2005 were included and subjected to detailed neuro-ophthalmologic examination and endoscopic endonasal optic nerve fenestration. Postoperative visual acuity and the perimetry was compared with the preoperative status, and the results were analyzed using the chi2 test. RESULTS:: Of the 18 patients included in the study, 17 had improvement in vision postoperatively. Fifteen patients had visual deterioration in the other eye as well, and of these, 12 had improvement, obviating the need for surgery on the other side. Complications were minimal and in the form of synechiae in two of the cases. DISCUSSION: A number of procedures have been described for the management of this entity, and each is associated with a significant morbidity; therefore, there was a need for a minimally invasive procedure. The procedure adopted in the series is minimally invasive and is associated with a 94.5% success rate and minimal morbidity. CONCLUSIONS: Endoscopic endonasal optic nerve fenestration is a safe, minimally invasive, and extremely effective procedure for the management of IIH.
机译:目的:研究内镜鼻内视神经开窗术治疗特发性颅内高压症(IIH)的有效性和安全性。设计:三级护理中心的前瞻性研究。患者与方法:纳入所有2001年7月至2005年3月最终诊断为IIH的患者,并接受详细的神经眼科检查和内镜鼻内视神经开窗术。将术后视力和视野检查与术前状态进行比较,并使用chi2检验分析结果。结果:在研究的18位患者中,有17位术后视力得到改善。 15例患者的另一只眼也出现视力下降,其中12例患者的病情得到了改善,从而避免了另一侧的手术需求。在两种情况下,并发症的发生率极低,并以粘连的形式出现。讨论:已经描述了许多用于管理该实体的程序,每个程序都具有很高的发病率。因此,需要一种微创手术。该系列中采用的程序具有最小的侵入性,并具有94.5%的成功率和最低的发病率。结论:内窥镜鼻内视神经开窗术是治疗IIH的安全,微创和极有效的方法。

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