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首页> 外文期刊>The American Journal of Cardiology >Clinical and Echocardiographic Features of Mitral Annular Calcium in Patients Aged <= 50 Years
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Clinical and Echocardiographic Features of Mitral Annular Calcium in Patients Aged <= 50 Years

机译：<= 50岁的二尖瓣环钙的临床和超声心动图特征

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Data regarding characteristics of young patients with mitral annular calcification (MAC) and its associations with other cardiovascular risk factors are scarce. Hence, we sought to characterize patients aged <50 years with MAC and to examine whether in these patients, MAC is also associated with cardiovascular risk factors. Consecutive patients who underwent an echocardiographic study were prospectively entered into a database. The database included clinical, laboratory, and echocardiographic parameters. The present study included 56 patients aged <50 years with a diagnosis of MAC. The mean age was 44.2+/-6.9 years with a male-to-female ratio of 2.5:1. The prevalence of cardiovascular risk factors (30 patients [53%] hypertension, 17 patients [30%] diabetes mellitus, 24 patients [43%] dyslipidemia, 22 patients [39%] smoking) and established cardiovascular disease (22 patients [39%] coronary artery disease,-11 patients [19%] previous stroke) was substantially higher than expected for this age group. Twenty-nine patients (52%) had chronic kidney disease. Of these, 18 patients (62%) had end-stage kidney disease and 7 patients (24%) underwent renal transplantation. Fourteen patients (25%) and 3 patients (5%) had moderate or severe mitral regurgitation and mitral stenosis, respectively. Aortic valve disease was present in 37 patients (66%). Moderate or severe left ventricular dysfunction and left ventricular hypertrophy were identified in 9 patients (16%) and 31 patients (56%), respectively. In conclusion, the detection of MAC in a young patient should be regarded as a marker of atherosclerotic disease, chronic kidney disease, and aortic valve disease. (C) 2015 Elsevier Inc. All rights reserved.
机译：关于年轻二尖瓣环钙化（MAC）患者的特征及其与其他心血管危险因素的关联的数据很少。因此，我们试图表征年龄小于50岁的MAC患者，并检查这些患者中MAC是否也与心血管危险因素相关。连续接受超声心动图检查的患者已输入数据库。该数据库包括临床，实验室和超声心动图参数。本研究包括56位年龄在50岁以下且诊断为MAC的患者。平均年龄为44.2 +/- 6.9岁，男女比例为2.5：1。心血管疾病危险因素（30例[53％]高血压，17例[30％]糖尿病，24例[43％]血脂异常，22例[39％]吸烟）的患病率和确诊的心血管疾病（22例[39％] ]冠状动脉疾病，-11例[19％]以前的卒中）大大高于该年龄组的预期。二十九名患者（52％）患有慢性肾脏病。其中，有18例（62％）患有终末期肾脏疾病，有7例（24％）接受了肾脏移植。二尖瓣关闭不全和二尖瓣狭窄分别为14例（25％）和3例（5％）。 37例患者（66％）存在主动脉瓣疾病。分别确定9例（16％）和31例（56％）的中度或重度左心室功能障碍和左心室肥大。总之，在年轻患者中检测到MAC应该被视为动脉粥样硬化疾病，慢性肾脏疾病和主动脉瓣疾病的标志。 （C）2015 Elsevier Inc.保留所有权利。

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