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首页> 外文期刊>The American Journal of Cardiology >Changes in right ventricular pressures between hemodialysis sessions recorded by an implantable hemodynamic monitor.
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Changes in right ventricular pressures between hemodialysis sessions recorded by an implantable hemodynamic monitor.

机译:植入式血流动力学监测仪记录的血液透析之间的右心室压力变化。

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Intermittent and chronic volume overload might contribute to the onset and progression of cardiovascular disease in patients who are undergoing maintenance hemodialysis (HD). Continuous monitoring of central hemodynamic variables may provide valuable information to improve volume control, particularly in patients with left ventricular dysfunction. Sixteen patients with end-stage renal disease who were undergoing long-term HD received an implantable hemodynamic monitor consisting of a subcutaneously implanted memory device and transvenous right ventricular (RV) lead with a pressure sensor. The implantable hemodynamic monitor continuously records heart rate, RV pressures, and estimated pulmonary arterial (PA) diastolic pressure, an estimate of left ventricular filling pressure. All patients underwent HD 3 times per week, and averages of rest hemodynamic values from the first, second, and third nights after HD during 12 weeks were analyzed. The third night always occurred after the weekend, when there wasan extended interval between dialysis sessions. From the first night to the second night, RV systolic pressure increased by 10 +/- 8% (p <0.001), and estimated PA diastolic pressure increased by 16 +/- 14% (p <0.001). On the third night, RV systolic pressure increased by 14 +/- 12% (p <0.001), and estimated PA diastolic pressure increased by 23 +/- 18% (p <0.001) compared with the first night. In conclusion, the progressive pressure increments between dialysis sessions seen in this study suggest that the implantable hemodynamic monitor was a sensitive indicator for changes in volume load in patients who were undergoing HD treatment. The results also suggest that more frequent dialysis may avoid excessive pressure increase, but this needs to be investigated further in future studies.
机译:间歇性和慢性容量超负荷可能会导致正在接受维持性血液透析(HD)的患者的心血管疾病的发作和进展。持续监测中心血流动力学变量可能会提供有价值的信息,以改善音量控制,尤其是对于左心功能不全的患者。接受长期HD治疗的16例终末期肾病患者接受了植入式血流动力学监测器,该监测器由皮下植入的存储设备和带压力传感器的右室右室(RV)导联组成。植入式血流动力学监测器连续记录心率,RV压力和估计的肺动脉(PA)舒张压,即左心室充盈压的估计值。所有患者每周接受HD 3次,分析HD在12周内第一,第二和第三晚的静息血液动力学值。第三天晚上总是发生在周末之后,那时透析时间间隔很长。从第一夜到第二夜,RV收缩压增加10 +/- 8%(p <0.001),估计的PA舒张压增加16 +/- 14%(p <0.001)。在第三天晚上,与第一天晚上相比,RV收缩压增加了14 +/- 12%(p <0.001),估计的PA舒张压增加了23 +/- 18%(p <0.001)。总之,在这项研究中看到的两次透析之间的渐进压力增加表明,植入式血流动力学监测仪是接受HD治疗的患者中容积负荷变化的敏感指标。结果还表明,更频繁的透析可以避免压力过度升高,但这需要在未来的研究中进一步研究。

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