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首页> 外文期刊>The American Journal of Cardiology >Echocardiographic parameters of mechanical synchrony in healthy individuals.
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Echocardiographic parameters of mechanical synchrony in healthy individuals.

机译：健康个体机械同步的超声心动图参数。

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Definition and validation of the ranges of normal values and agreement among echocardiographic measures of mechanical synchrony in healthy subjects are mostly lacking. The aims of this study were (1) to assess the ranges of normal values for 5 tissue Doppler imaging parameters, real-time 3-dimensional echocardiographic measures, and speckle-tracking measures of mechanical synchrony; (2) to evaluate interinstitutional variability; (3) to compare the ranges of normal values with those reported in previous research; and (4) to analyze the agreement among all parameters in the same healthy subject. Time to peak systolic velocity (Ts), the delay between Ts at the basal septal and lateral segments, peak velocity difference, strain derived by tissue Doppler imaging, Ts derived by tissue synchronization imaging, systolic synchrony index (SSI) derived by real-time 3-dimensional echocardiography, and longitudinal and radial strain derived by speckle tracking were prospectively collected and analyzed at 2 different institutions in 160 consecutive healthy subjects. The ranges of normal values, expressed as means +/- 2 SDs, were 30.32 +/- 29.36 ms for the SD of Ts, 15.51 +/- 99.88 ms for septal-lateral delay, 60.75 +/- 81.62 ms for peak velocity difference, 33.07 +/- 29.96 ms for tissue synchronization imaging, 34.16 +/- 23.26 ms for the SD of strain, 2.74 +/- 2.16% for SSI, 28.91 +/- 23.02 ms for the SD of longitudinal strain, and 10.4 +/- 6.31 ms for radial strain. There was large interinstitutional variability for all parameters. Three-dimensional SSI and radial strain were within the published upper range limit for healthy subjects. Ninety percent of healthy subjects were consistently classified to be synchronous by 1 parameter. With a composite index, more subjects than expected showed dyssynchrony (10% vs 2.5%). In conclusion, 3-dimensional SSI and radial strain were the most reproducible parameters and consistently discriminated normal healthy subjects from the cardiac resynchronization therapy volume responders.
机译：在健康受试者中，通常缺乏正常值范围的定义和验证以及超声心动图机械同步性测量之间的一致性。这项研究的目的是（1）评估5个组织多普勒成像参数，实时3维超声心动图测量值以及机械同步的斑点跟踪测量值的正常值范围; （2）评估机构间的可变性; （3）将正常值的范围与先前研究中报道的范围进行比较; （4）分析同一健康受试者中所有参数之间的一致性。达到峰值收缩时间（Ts）的时间，基底间隔和外侧节段的Ts之间的延迟，峰值速度差，通过组织多普勒成像得出的应变，通过组织同步成像得出的Ts，通过实时得出的收缩同步指数（SSI）前瞻性收集并通过160个连续健康受试者的2个不同机构对3维超声心动图以及通过斑点跟踪得出的纵向和径向应变进行了分析。正常值的范围表示为平均值+/- 2 SDs，Ts的SD值为30.32 +/- 29.36 ms，间隔-侧向延迟为15.51 +/- 99.88 ms，峰值速度差为60.75 +/- 81.62 ms ，对于组织同步成像为33.07 +/- 29.96 ms，对于应变SD为34.16 +/- 23.26 ms，对于SSI为2.74 +/- 2.16％，对于纵向应变SD为28.91 +/- 23.02 ms，以及10.4 + / -径向应变为6.31毫秒。所有参数的机构间差异都很大。三维SSI和径向应变在健康受试者的已公布上限范围内。 90％的健康受试者始终被1个参数归类为同步。有了综合指数，比预期多的受试者表现出不同步（10％比2.5％）。总之，3维SSI和径向应变是最可重复的参数，并且始终将正常健康受试者与心脏再同步治疗量反应者区分开。

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