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首页> 外文期刊>The American Journal of Cardiology >Drug-eluting stents in heart transplant recipients.
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Drug-eluting stents in heart transplant recipients.

机译:心脏移植接受者的药物洗脱支架。

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摘要

We read with great interest the work of Gupta et al in which they reported on 32 heart transplant recipients at their institution who were treated with drug-eluting stents (DES) for cardiac allograft vasculopathy (CAV) and retrospectively followed for 1.3 +- 1.2 years. During follow-up, 12 patients (38%) died, 1 (3%) underwent retransplantation, 4 (13%) underwent revascularization, and 5 of 21 patients (24%) who underwent coronary angiography had in-stent restenosis. The investigators also compared their data with a historical control of 35 patients with CAV treated with bare-metal stents (BMS). At 1 year, survival was not different between DES (68%) and BMS (91%) after adjustments for baseline characteristics. The restenosis rate was lower with DES (19%) than BMS (49%). Gupta et al concluded that in this "largest single-institution series of DES use" in patients with CAV, DES were associated with lower in-stent restenosis than BMS but that the survival of these patients was particularly poor and not affected by DES use.
机译:我们非常感兴趣地阅读了Gupta等人的工作,他们报告了他们所在机构的32名心脏移植受者,他们接受了药物洗脱支架(DES)治疗的同种异体移植血管病(CAV),并回顾了1.3±1.2年。在随访期间,有12例患者(38%)死亡,1例(3%)接受了移植,4例(13%)进行了血管重建,21例接受冠状动脉造影的患者中有5例发生了支架内再狭窄。研究人员还将他们的数据与35例接受裸金属支架(BMS)治疗的CAV患者的历史对照进行了比较。调整基线特征后,DES(68%)和BMS(91%)的生存期无差异。 DES(19%)的再狭窄率低于BMS(49%)。 Gupta等人得出结论,在CAV患者的“最大的单机构使用DES系列”研究中,与BMS相比,DES与支架内再狭窄的发生率相关,但这些患者的生存特别差,不受DES使用的影响。

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