...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >A prospective study of cardiovascular risk factors and incident hearing loss in men.
【24h】

A prospective study of cardiovascular risk factors and incident hearing loss in men.

机译：男性心血管危险因素和事件性听力损失的前瞻性研究。

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVES/HYPOTHESIS: Hearing loss is the most common sensory disorder in the United States, affecting more than 36 million people. Cardiovascular risk factors have been associated with the risk of hearing loss in cross-sectional studies, but prospective data are currently lacking. STUDY DESIGN: Prospective cohort study. METHODS: We prospectively evaluated the association between diagnosis of hypertension, diabetes mellitus, hypercholesterolemia, smoking, or body mass index (BMI) and incident hearing loss. Participants were 26,917 men in the Health Professionals Follow-up Study, aged 40 to 74 years at baseline in 1986. Study participants completed questionnaires about lifestyle and medical history every 2 years. Information on self-reported professionally diagnosed hearing loss and year of diagnosis was obtained from the 2004 questionnaire, and cases were defined as hearing loss diagnosed between 1986 and 2004. Multivariable-adjusted hazard ratios (HRs) were calculated using Cox proportional hazards regression models. RESULTS: A total of 3,488 cases of hearing loss were identified. History of hypertension (HR 0.96; 95% confidence interval [CI], 0.88-1.03), diabetes mellitus (HR 0.92; 95% CI, 0.78-1.08), or obesity (HR 1.02; 95% CI, 0.90-1.15 for BMI >or=30 compared to normal range of 19-24.9) was not significantly associated with hearing-loss risk. Hypercholesterolemia (HR 1.10; 95% CI, 1.02-1.18) and past smoking history (HR 1.09; 95% CI, 1.01-1.17) were associated with a significantly increased risk of hearing loss after multivariate adjustment. CONCLUSIONS: A history of hypertension, diabetes mellitus, or obesity is not associated with increased risk of hearing loss; a history of past smoking or hypercholesterolemia has a small but statistically significant association with increased risk of hearing loss in adult males.
机译：目的/假设：听力损失是美国最常见的感觉障碍，影响了超过3600万人。在横断面研究中，心血管危险因素与听力下降的风险有关，但目前尚缺乏前瞻性数据。研究设计：前瞻性队列研究。方法：我们前瞻性评估了高血压，糖尿病，高胆固醇血症，吸烟或体重指数（BMI）的诊断与事件性听力损失之间的关联。 1986年，健康专业人士随访研究的参与者为26,917名男性，基线年龄为40至74岁。研究参与者每两年完成一次有关生活方式和病史的问卷调查。从2004年的调查表中获得有关自我报告的专业诊断性听力损失和诊断年份的信息，并将病例定义为1986年至2004年之间诊断的听力损失。使用Cox比例风险回归模型计算多变量调整的危险比（HRs）。结果：总共鉴定出3488例听力损失病例。高血压史（HR 0.96; 95％置信区间[CI]，0.88-1.03），糖尿病（HR 0.92; 95％CI，0.78-1.08）或肥胖病史（HR 1.02; 95％CI，0.90-1.15）与正常范围19-24.9相比 = 30）与听力损失风险没有显着相关。高胆固醇血症（HR 1.10; 95％CI，1.02-1.18）和既往吸烟史（HR 1.09; 95％CI，1.01-1.17）与多变量调整后听力损失的风险显着相关。结论：高血压，糖尿病或肥胖病史与听力损失风险增加无关;既往吸烟或高胆固醇血症的病史与成年男性听力损失风险增加之间的关联很小，但在统计学上具有显着意义。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号