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首页> 外文期刊>The American Journal of Cardiology >Prevalence of heart failure with preserved ejection fraction in Latin American, Middle Eastern, and North African Regions in the I PREFER study (Identification of Patients With Heart Failure and PREserved Systolic Function: an epidemiological regional study).
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Prevalence of heart failure with preserved ejection fraction in Latin American, Middle Eastern, and North African Regions in the I PREFER study (Identification of Patients With Heart Failure and PREserved Systolic Function: an epidemiological regional study).

机译：在I PREFER研究中（拉丁美洲，中东和北非地区心力衰竭患儿射血分数保持不变）（识别心力衰竭和收缩功能正常的患者：一项流行病学区域研究）。

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摘要

The aims of the present study were to estimate the prevalence of heart failure (HF) with preserved ejection fraction (HF-PEF) in patients with HF and to compare their clinical characteristics with those with reduced ejection fraction in non-Western countries. The left ventricular ejection fraction >/= 45% if measured < 1 year before the visit was used to qualify the patients as having HF-PEF. Of the 2,536 consecutive outpatients with HF, 1990 (79%) had the EF values recorded. Of these patients, 1291 had HF-PEF, leading to an overall prevalence of 65% (95% confidence interval 63% to 67%). Compared to the patients with HF and a reduced ejection fraction, those with HF-PEF were more likely to be older (65 vs 62 years, p < 0.001), female (50% vs 28%, p < 0.001), and obese (39% vs 27%, p < 0.001). They more frequently had a history of hypertension (78% vs 53%, p < 0.001) and atrial fibrillation (29% vs 24%, p = 0.03) and less frequently had a history of myocardial infarction (21% vs 44%, p < 0.001). Only 29% of patients with HF-PEF and hypertension had optimal blood pressure control. Left ventricular hypertrophy was less frequent in those with HF-PEF (58% vs 69%, p < 0.001). The prevalence of HF-PEF was lower in the Middle East (41%), where coronary artery disease was more often found than in Latin America (69%) and North Africa (75%), where the rate of hypertension was greater. In conclusion, in the present diverse non-Western study, HF-PEF represented almost 2/3 of all HF cases in outpatients. HF-PEF mostly affects older patients, women, and the obese. Hypertension was the most frequently associated risk factor, highlighting the need for optimal blood pressure control.
机译：本研究的目的是评估心力衰竭（HF）射血分数保留（HF-PEF）的患病率，并将其临床特征与非西方国家射血分数降低的患者进行比较。如果在访视前<1年测量，则左心室射血分数> / = 45％，可用于确定患者是否患有HF-PEF。在2,536名连续性HF患者中，1990年（79％）的EF值记录在案。在这些患者中，有1291名患有HF-PEF，导致总体患病率为65％（95％的置信区间为63％至67％）。与HF和射血分数降低的患者相比，HF-PEF的患者年龄更大（65岁vs 62岁，p <0.001），女性（50％vs 28％，p <0.001）和肥胖（ 39％和27％，p <0.001）。他们有高血压病史（78％vs 53％，p <0.001）和心房颤动（29％vs 24％，p = 0.03）的频率更高，有心肌梗塞病史（21％vs 44％，p <0.001）。只有29％的HF-PEF和高血压患者具有最佳的血压控制。 HF-PEF患者左心室肥大的发生率较低（58％vs 69％，p <0.001）。 HF-PEF的患病率较低的是中东（41％），那里的冠状动脉疾病多见，而拉丁美洲（69％）和北非（75％）的高血压发生率更高。总之，在目前的各种非西方研究中，门诊患者中HF-PEF几乎占所有HF患者的2/3。 HF-PEF主要影响老年患者，女性和肥胖者。高血压是最常见的危险因素，突显了对最佳血压控制的需求。

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