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首页> 外文期刊>The American Journal of Cardiology >Frequency of intensive statin therapy in patients with acute coronary syndrome admitted to a tertiary care center
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Frequency of intensive statin therapy in patients with acute coronary syndrome admitted to a tertiary care center

机译：三级护理中心收治的急性冠脉综合征患者强化他汀类药物治疗的频率

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Intensive statin therapy (IST) has been shown to decrease cardiovascular events in patients with acute coronary syndrome (ACS). Numerous studies have described statin use for secondary prevention; however, few data have highlighted IST use after ACS. The objective of the present study was to describe IST use in an ACS population before hospitalization, on discharge, and during early follow-up after discharge. A retrospective chart review was conducted of randomly selected patients admitted to a tertiary care center from November 1, 2007 to October 31, 2008. Eligible patients included adults admitted to cardiology with a most responsible diagnosis of ACS (International Classification of Diseases code 20-25). The exclusion criteria included transfer to another hospital or cardiovascular surgery ward and in-hospital death. Phase 1 included an inpatient chart review. Phase 2 was a follow-up cardiologist clinic letter review that included only patients who started IST in-hospital. Of 234 charts reviewed, 111 (47%) patients met the inclusion criteria (mean age 65 ± 11.7 years, 76% men). Most patients (93%) were discharged with a statin. However, although 72% of the study population were eligible for IST, only 52% had IST during hospitalization. Of the patients who started IST with clinic letters available (n = 31), 68% continued IST (mean interval to follow-up 85 days, range 33 to 208). In conclusion, although statin use is good, IST use after ACS is suboptimal. Additionally, newly initiated IST demonstrates poor persistence after discharge.
机译：他汀类药物强化治疗（IST）已显示可减少急性冠脉综合征（ACS）患者的心血管事件。许多研究已经描述了他汀类药物在二级预防中的用途。但是，很少有数据强调ACS后IST的使用。本研究的目的是描述IST在住院，出院时以及出院后早期随访期间在ACS人群中的使用情况。对2007年11月1日至2008年10月31日入住三级护理中心的随机选择患者进行回顾性图表审查。符合条件的患者包括接受心脏病学诊断为ACS最负责的成年人（国际疾病分类代码20-25） ）。排除标准包括转移到另一家医院或心血管外科病房和住院死亡。第一阶段包括住院图表检查。第2阶段是心脏科医师诊所的随访信，包括仅在医院内开始IST的患者。在234张检查的图表中，有111名（47％）患者符合纳入标准（平均年龄65±11.7岁，男性76％）。大多数患者（93％）出院后都服用他汀类药物。但是，尽管有72％的研究人群符合IST的资格，但只有52％的人在住院期间患有IST。在有临床证明信的情况下开始IST的患者中（n = 31），继续进行IST的患者为68％（平均随访时间85天，范围为33至208）。总之，尽管他汀类药物的使用良好，但ACS后的IST使用效果欠佳。此外，新启动的IST显示出院后持久性差。

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