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首页> 外文期刊>The American Journal of Cardiology >Serial gray scale intravascular ultrasound findings in late drug-eluting stent restenosis
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Serial gray scale intravascular ultrasound findings in late drug-eluting stent restenosis

机译：晚期药物洗脱支架再狭窄中的系列灰度血管内超声检查结果

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摘要

The primary aim of the present study was to assess the gray scale intravascular ultrasound (IVUS) findings that might be associated with late drug-eluting stent restenosis. The study included 47 patients (54 lesions) who had undergone either baseline IVUS-guided stent implantation or IVUS-guided repeat stenting to treat in-stent restenosis and then had IVUS follow-up data for ??1.5 years afterward without any intervening procedures. The left anterior descending artery was the culprit in 59% of cases, and 50% of the lesions were at bifurcation sites. Quantitative and qualitative IVUS analyses showed a decreased minimum lumen area at follow-up from 6.0 ?? 1.8 to 3.8 ?? 1.4 mm2 (p 0.0001) that was mainly due to neointimal hyperplasia with chronic stent recoil (defined as a 15% decrease in minimum stent area) in only 2 lesions and stent fracture in only 5 lesions. Calcified neointima appeared in 12 lesions, mostly in the form of macrocalcification, and was associated with increased calcium both behind the stent and in the reference segment. In conclusion, late drug-eluting stent restenosis showed neointimal calcification in 20% of cases, and chronic stent recoil was rare. ? 2013 Elsevier Inc. All rights reserved.
机译：本研究的主要目的是评估可能与晚期药物洗脱支架再狭窄有关的灰度血管内超声（IVUS）发现。该研究包括47例（54个病灶）患者，他们接受了基线IVUS引导的支架植入术或IVUS引导的重复性支架植入术治疗支架内再狭窄，然后在1.5年后进行了IVUS随访数据，而没有任何干预措施。左前降支动脉是罪魁祸首，占59％，病变的50％位于分叉部位。定量和定性IVUS分析显示，随访时最小管腔面积从6.0 ??降低。 1.8至3.8 ?? 1.4 mm2（p <0.0001），主要是由于新内膜增生伴有慢性支架回缩（定义为最小支架面积减少> 15％），仅2个病变，仅5个病变。钙化的新内膜出现在12个病变中，大部分以宏观钙化的形式出现，并且与支架后和参考节段中钙的增加有关。总之，晚期药物洗脱支架再狭窄在20％的病例中表现为新内膜钙化，而慢性支架后坐力很少见。 ？ 2013 Elsevier Inc.保留所有权利。

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