...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The American Journal of Cardiology >Relation between six-minute walk test performance and outcomes after transcatheter aortic valve implantation (from the PARTNER Trial)
【24h】

Relation between six-minute walk test performance and outcomes after transcatheter aortic valve implantation (from the PARTNER Trial)

机译：经导管主动脉瓣植入后六分钟步行测试性能与预后之间的关系（来自PARTNER试验）

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Functional capacity as assessed by 6-minute walk test distance (6MWTD) has been shown to predict outcomes in selected cohorts with cardiovascular disease. To evaluate the association between 6MWTD and outcomes after transcatheter aortic valve implantation (TAVI) among participants in the Placement of AoRTic TraNscathetER valve (PARTNER) trial, TAVI recipients (n = 484) were stratified into 3 groups according to baseline 6MWTD: unable to walk (n = 218), slow walkers (n = 133), in whom 6MWTD was below the median (128.5 meters), and fast walkers (n = 133) with 6MWTD >128.5 meters. After TAVI, among fast walkers, follow-up 6MWTD decreased by 44 ± 148 meters at 12 months (p <0.02 compared with baseline). In contrast, among slow walkers, 6MWTD improved after TAVI by 58 ± 126 meters (p <0.001 compared with baseline). Similarly, among those unable to walk, 6MWTD distance increased by 66 ± 109 meters (p <0.001 compared with baseline). There were no differences in 30-day outcomes among 6MWTD groups. At 2 years, the rate of death from any cause was 42.5% in those unable to walk, 31.2% in slow walkers, and 28.8% in fast walkers (p = 0.02), driven primarily by differences in noncardiac death. In conclusion, among high-risk older adults undergoing TAVI, baseline 6MWTD does not predict procedural outcomes but does predict long-term mortality. Nonetheless, patients with poor baseline functional status exhibit the greatest improvement in 6MWTD. Additional work is required to identify those with poor functional status who stand to benefit the most from TAVI.
机译：通过6分钟步行测试距离（6MWTD）评估的功能能力已显示出可预测某些心血管疾病队列的结局。为了评估AoRTic TraNscathetER瓣膜放置（PARTNER）试验参与者中经导管主动脉瓣植入（TAVI）后6MWTD与预后之间的关系，根据基线6MWTD将TAVI接受者（n = 484）分为3组：无法行走（n = 218），慢步行者（n = 133）和6MWTD> 128.5米的慢步行者（n = 133），其中6MWTD低于中位数（128.5米）。 TAVI后，快速步行者在12个月时的随访6MWTD下降了44±148米（与基线相比，p <0.02）。相反，在慢速步行者中，TAVI后6MWTD改善了58±126米（与基线相比，p <0.001）。同样，在那些无法行走的人中，6MWTD距离增加了66±109米（与基线相比，p <0.001）。 6MWTD组之间的30天结果无差异。在2年时，由于非心脏死亡的差异，导致无法行走者死于各种原因的死亡率为42.5％，缓慢行走者为31.2％，快速行走者为28.8％（p = 0.02）。总之，在接受TAVI的高危老年人中，基线6MWTD不能预测手术结果，但可以预测长期死亡率。但是，基线功能状态较差的患者在6MWTD方面表现出最大的改善。需要进行更多的工作来确定那些功能状况不佳的人，这些人将从TAVI中受益最大。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号