...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The American Journal of Cardiology >Is the 'rare' takotsubo syndrome a common affliction?
【24h】

Is the 'rare' takotsubo syndrome a common affliction?

机译：“罕见” takotsubo综合征是一种常见病吗？

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Takotsubo syndrome (ITS) was first described in 1991, and as of October 12, 2012, there are 1,450 entries in PubMed retrievable using the inquiry term "Takotsubo syndrome". Reading this avalanche of relevant research, mostly case reports, provides a stereotypical take on TTS: women are mostly afflicted, by a ratio to men of >6:1; patients in the original descriptions were mostly Japanese; the illness emerges in the "heat" of some psychological, physical, or other disease-related upheaval of varying intensity; apical "ballooning" due to dyskinesia, associated with ahyperkinetic left ventricular (LV) base, and marked decrease of the LV ejection fraction are detected by transthoracic echocardiog-raphy or contrast left ventriculography; the coronary arteries are normal, or they reveal nonobstructive coronary artery disease (CAD); there is severe, localized impairment of the microcirculation; electrocardiography shows ST-segment elevation or ST-segment depression with associated T-wave inversions and QT interval prolongation, with the T-wave inversions sometimes lingering for several weeks; there are modest, for the degree of LV dysfunction, transient increases in myocardial biomarkers; there are only a few distinguishing features between TTC and acute coronary syndromes, but they are not false proof, and they become apparent later in the course; there is full recovery of LV function within days to weeks at follow-up; there is no recurrence of TTS during short-term follow-up; mortality is rare, but morbidity is substantial and similar to that encountered in patients with acute coronary syndromes; and most patients respond to supportive, nonspecific care.
机译：Takotsubo综合征（ITS）于1991年首次被描述，截至2012年10月12日，使用查询词“ Takotsubo综合征”可检索到1,450个PubMed条目。阅读有关研究（主要是案例报告）的大量雪崩，对TTS产生了定型看法：女性受苦最大，男性比例> 6：1;原始描述中的患者大多是日本人;该疾病是由于某种程度的心理，身体或其他与疾病相关的剧变的“热”而出现的;经胸超声心动图或对比左心室造影可检测到运动障碍引起的根尖“膨胀”，并伴有运动亢进的左心室（LV）基底，并且左室射血分数明显降低。冠状动脉正常，或显示无阻塞性冠状动脉疾病（CAD）;微循环存在严重的局部损害;心电图显示ST段抬高或ST段压低，伴有T波倒置和QT间隔延长，有时T波倒置持续数周。对于左室功能障碍的程度，心肌生物标志物的短暂升高是适度的。 TTC和急性冠状动脉综合征之间只有少数区别特征，但它们并不是虚假的证据，并且在病程后期会变得明显。随访后数天至数周内，左室功能完全恢复;在短期随访中TTS没有复发;死亡率很少，但发病率很高，与急性冠脉综合征患者所见相似。大多数患者对支持性的非特异性治疗有反应。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号