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首页> 外文期刊>The American Journal of Cardiology >Meta-Analysis of Abdominal Aortic Aneurysm in Patients With Coronary Artery Disease
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Meta-Analysis of Abdominal Aortic Aneurysm in Patients With Coronary Artery Disease

机译:冠状动脉疾病患者腹主动脉瘤的Meta分析

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The high coronary artery disease (CAD) prevalence in patients with abdominal aortic aneurysm (AAA) is well known. However, the inverse relation has been little explored. We present, based on a systematic review and meta-analysis of the published evidence, a critical appraisal of the issue of AAA prevalence and also AAA predictive risk factors in patients with CAD, comparing it with AAA prevalence in subjects without CAD. A total of 22 studies involving 13,388 patients with CAD met the inclusion criteria. Overall, AAA prevalence in patients with CAD was 8.4% (95% confidence interval [CI] 6.9 to 10.3), significantly higher than in subjects without CAD (odds ratio [OR] 2.42, 95% CI 2.08 to 2.81). Pooled analysis revealed that smoking, arterial hypertension, and concomitant carotid artery stenosis were significantly associated with AAA in patients with CAD (OR 1.72, 95% CI 1.14 to 2.61; OR 1.57, 95% CI 1.06 to 2.35; OR 2.14, 95% CI 1.20 to 3.79, respectively). In patients with CAD, AAA prevalence tended to be higher with concomitant peripheral artery disease (OR 2.66, 95% CI 0.82 to 8.61, p = 0.08). In conclusion, AAA prevalence was significantly higher in patients with CAD versus subjects without CAD. (C) 2015 Elsevier Inc. All rights reserved.
机译:腹主动脉瘤(AAA)患者的冠状动脉疾病(CAD)高患病率是众所周知的。但是,反关系很少被探索。基于对已发表证据的系统评价和荟萃分析,我们对患有CAD的患者中AAA患病率以及AAA预测危险因素进行了严格评估,并将其与没有CAD的受试者中AAA患病率进行了比较。共有22项研究纳入13388名CAD患者,符合纳入标准。总体而言,CAD患者的AAA患病率为8.4%(95%置信区间[CI] 6.9至10.3),显着高于没有CAD的受试者(优势比[OR] 2.42,95%CI 2.08至2.81)。汇总分析显示,CAD患者的AAA与吸烟,动脉高压和伴随的颈动脉狭窄显着相关(OR 1.72,95%CI 1.14至2.61; OR 1.57,95%CI 1.06至2.35; OR 2.14,95%CI分别为1.20至3.79)。在患有CAD的患者中,伴随外周动脉疾病的AAA患病率较高(OR 2.66,95%CI 0.82至8.61,p = 0.08)。总之,患有CAD的患者的AAA患病率明显高于没有CAD的患者。 (C)2015 Elsevier Inc.保留所有权利。

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