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首页> 外文期刊>The American Journal of Cardiology >Associations Between Day of Admission and Day of Surgery on Outcome and Resource Utilization in Infants With Hypoplastic Left Heart Syndrome Who Underwent Stage I Palliation (from the Single Ventricle Reconstruction Trial)
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Associations Between Day of Admission and Day of Surgery on Outcome and Resource Utilization in Infants With Hypoplastic Left Heart Syndrome Who Underwent Stage I Palliation (from the Single Ventricle Reconstruction Trial)

机译:接受I期姑息治疗的发育不良左心综合征的婴儿入院日与手术日之间结局和资源利用的关系(来自单心室重建试验)

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Newborns with hypoplastic left heart syndrome and other single right ventricular variants require substantial health care resources. Weekend acute care has been associated with worse outcomes and increased resource use in other populations but has not been studied in patients with single ventricle. Subjects of the Single Ventricle Reconstruction trial were classified by whether they had a weekend admission and by day of the week of Norwood procedure. The primary outcome was hospital length of stay (LOS); secondary outcomes included transplant-free survival, intensive care unit (ICU) LOS, and days of mechanical ventilation. The Student's t test with log transformation and the Wilcoxon rank-sum test were used to analyze associations. Admission day was categorized for 533 of 549 subjects (13% weekend). The day of the Norwood was Thursday/Friday in 39%. There was no difference in median hospital LOS, transplant-free survival, ICU LOS, or days ventilated for weekend versus non-weekend admissions. Day of the Norwood procedure was not associated with a difference in hospital LOS, transplant-free survival, ICU LOS, or days ventilated. Prenatally diagnosed infants born on the weekend had lower mean birth weight, younger gestational age, and were more likely to be intubated but did not have a difference in measured outcomes. In conclusion, in this cohort of patients with single right ventricle, neither weekend admission nor end-of-the-week Norwood procedure was associated with increased use of hospital resources or poorer outcomes. We speculate that the complex postoperative course following the Norwood procedure outweighs any impact that day of admission or operation may have on these outcomes. (C) 2015 Elsevier Inc. All rights reserved.
机译:患有左心发育不全和其他单个右心室变异的新生儿需要大量的医疗保健资源。周末急性护理与其他人群的结局恶化和资源使用增加有关,但尚未对单心室患者进行研究。根据是否有周末入院和诺伍德手术的星期几对单心室重建试验的受试者进行分类。主要结果是住院时间(LOS);次要结果包括无移植生存,重症监护病房(LOS)和机械通气天数。使用具有对数变换的Student t检验和Wilcoxon秩和检验来分析关联。 549名受试者中的533名入学日(周末占13%)。诺伍德节那天是星期四/星期五,占39%。周末入院与非周末入院的中位住院LOS,无移植存活率,ICU LOS或通气天数无差异。诺伍德手术的天数与医院LOS,无移植生存期,ICU LOS或通气天数的差异无关。在周末出生的产前诊断婴儿平均出生体重较低,胎龄更小,更可能插管,但测量结果无差异。总之,在这组右室单一的患者中,周末入院或每周末Norwood手术均与增加医院资源使用或不良预后相关。我们推测,诺伍德手术后的复杂术后过程超过了入院或手术当天对这些结果的任何影响。 (C)2015 Elsevier Inc.保留所有权利。

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