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首页> 外文期刊>The American Journal of Clinical Nutrition: Official Journal of the American Society for Clinical Nutrition >Dietary intake and status of n-3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters, vegetarians, and vegans and the product-precursor ratio (corrected) of alpha-linolenic acid to long-chain n-3 polyunsaturated fatty acids: results from the EPIC-Norfolk cohort.
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Dietary intake and status of n-3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters, vegetarians, and vegans and the product-precursor ratio (corrected) of alpha-linolenic acid to long-chain n-3 polyunsaturated fatty acids: results from the EPIC-Norfolk cohort.

机译:吃鱼和不吃鱼的肉食者,素食主义者和素食主义者的饮食中n-3多不饱和脂肪酸的摄入量和状况以及α-亚麻酸与长链的乘积比(校正) n-3多不饱和脂肪酸:来自EPIC-Norfolk研究组。

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BACKGROUND: Intakes of n-3 (omega-3) polyunsaturated fatty acids (PUFAs) are important for health. Because fish is the major source of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), non-fish-eaters may have suboptimal n-3 PUFA status, although the importance of the conversion of plant-derived alpha-linolenic acid (ALA) to EPA and DHA is debated. OBJECTIVE: The objective was to determine intakes, food sources, and status of n-3 PUFAs according to dietary habit (fish-eaters and non-fish-eating meat-eaters, vegetarians, or vegans) and estimated conversion between dietary ALA and circulating long-chain n-3 PUFAs. DESIGN: This study included 14,422 men and women aged 39-78 y from the EPIC (European Prospective Investigation into Cancer and Nutrition)-Norfolk cohort with 7-d diary data and a substudy in 4902 individuals with plasma phospholipid fatty acid measures. Intakes and status of n-3 PUFAs were measured, and the product-precursor ratio [corrected] of ALA to circulating n-3 PUFAs was calculated. RESULTS: Most of the dietary intake of EPA and DHA was supplied by fish; however, meat was the major source in meat-eaters, and spreading fats, soups, and sauces were the major sources in vegetarians. Total n-3 PUFA intakes in non-fish-eaters were 57-80% of those in fish-eaters, but status differences were considerably smaller [corrected]. The estimated product-precursor ratio [corrected] was greater in women than in men and greater in non-fish-eaters than in fish-eaters. CONCLUSIONS: Substantial differences in intakes and in sources of n-3 PUFAs existed between the dietary-habit groups, but the differences in status were smaller than expected, possibly because the product-precursor ratio [corrected] was greater in non-fish-eaters than in fish-eaters, potentially indicating increased estimated conversion of ALA. If intervention studies were to confirm these findings, it could have implications for fish requirements.
机译:背景:n-3(omega-3)多不饱和脂肪酸(PUFA)的摄入对于健康很重要。由于鱼类是二十碳五烯酸(EPA)和二十二碳六烯酸(DHA)的主要来源,因此非食用鱼类的n-3 PUFA状况可能欠佳,尽管转化植物来源的α-亚麻酸(ALA)的重要性EPA和DHA的争议。目的:目的是根据饮食习惯(食鱼者和不食鱼的肉食者,素食者或素食者)以及饮食ALA和循环饮食之间的转换来确定n-3 PUFA的摄入量,食物来源和状况长链n-3 PUFA。设计:本研究包括来自EPIC(欧洲癌症和营养学前瞻性调查)-诺福克队列研究的14422名年龄在39-78岁之间的男性和女性,该研究具有7d日记数据,并对4902名接受血浆磷脂脂肪酸测定的个体进行了研究。测量了n-3 PUFA的摄入量和状态,并计算了ALA与循环n-3 PUFA的乘积比[校正]。结果:EPA和DHA的大部分饮食摄入是由鱼提供的。但是,肉是食肉者的主要来源,而散布的脂肪,汤和酱汁则是素食者的主要来源。非食鱼者中n-3 PUFA的总摄入量为食鱼者中的57-80%,但状态差异要小得多[已校正]。妇女的估计产品前体比率(校正)比男子大,非食鱼者比食鱼者更大。结论:在饮食习惯组之间,n-3 PUFA的摄入量和来源存在实质性差异,但状态差异小于预期,这可能是因为非鱼食者的产品前体比[校正后]更大比食鱼者要多,这可能表示估计的ALA转化率增加。如果干预研究证实这些发现,可能会对鱼类的需求产生影响。

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