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首页> 外文期刊>The Journal of Physiology >A new answer to an old question: does ageing modify baroreflex control of vascular sympathetic outflow in humans?
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A new answer to an old question: does ageing modify baroreflex control of vascular sympathetic outflow in humans?

机译:一个老问题的新答案:衰老会改变人体对血管交感神经流出的压力反射控制吗?

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摘要

The baroreflexes are the primary neural mechanism by which arterial blood pressure (BP) is regulated on a beat-by-beat basis. Over 100 years of research has provided great insight into the structure and function of the baroreflexes in both health and disease (Eckberg & Sleight, 1992). In humans baroreflex function is commonly quantified by assessing changes in R-R interval or vascular sympathetic outflow during dynamic increases and/or decreases in BR With advancing age, it is well accepted that baroreflex modulation of R-R interval is depressed (Monahan, 2007). In contrast, although less thoroughly studied, baroreflex control of vascular sympathetic outflow is generally believed to be unchanged with advancing age (Monahan, 2007).
机译:压力反射是主要的神经机制,通过该机制可以逐次调节动脉血压(BP)。超过100年的研究提供了对健康和疾病中压力反射的结构和功能的深刻见解(Eckberg&Sleight,1992)。在人类中,压力反射反射功能通常通过评估BR的动态增加和/或减小过程中R-R间隔或血管交感神经流出的变化来量化,随着年龄的增长,R-R间隔的压力反射反射调节被抑制是公认的(Monahan,2007)。相比之下,尽管研究还不够深入,但人们普遍认为,随着年龄的增长,血管交感神经流出的压力感受反射控制不会改变(Monahan,2007)。

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