• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Journal of Experimental Biology >Mixed input to olfactory glomeruli from two subsets of ciliated sensory neurons does not impede relay neuron specificity in the crucian carp
【24h】

Mixed input to olfactory glomeruli from two subsets of ciliated sensory neurons does not impede relay neuron specificity in the crucian carp

机译：来自纤毛感觉神经元的两个子集的嗅觉肾小球的混合输入不会阻碍the鱼的中继神经元特异性

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The consensus view of olfactory processing is that the axons of receptor-specific primary olfactory sensory neurons (OSNs) converge to a small subset of glomeruli, thus preserving the odour identity before the olfactory information is processed in higher brain centres. In the present study, we show that two different subsets of ciliated OSNs with different odorant specificities converge to the same glomeruli. In order to stain different ciliated OSNs in the crucian carp Carassius carassius we used two different chemical odorants, a bile salt and a purported alarm substance, together with fluorescent dextrans. The dye is transported within the axons and stains glomeruli in the olfactory bulb. Interestingly, the axons from the ciliated OSNs co-converge to the same glomeruli. Despite intermingled innervation of glomeruli, axons and terminal fields from the two different subsets of ciliated OSNs remained mono-coloured. By 4-6 days after staining, the dye was transported trans-synaptically to separately stained axons of relay neurons. These findings demonstrate that specificity of the primary neurons is retained in the olfactory pathways despite mixed innervation of the olfactory glomeruli. The results are discussed in relation to the emerging concepts about non-mammalian glomeruli.
机译：嗅觉处理的共识观点是，受体特异性初级嗅觉感觉神经元（OSN）的轴突会聚到一小部分肾小球，从而在嗅觉信息在较高的大脑中心进行处理之前保留气味的同一性。在本研究中，我们显示具有不同气味特异性的纤毛OSN的两个不同子集会聚到同一肾小球。为了对the鱼的不同纤毛OSN进行染色，我们使用了两种不同的化学增味剂，胆汁盐和声称的报警物质，以及荧光葡聚糖。染料在轴突内运输，并在嗅球中染色肾小球。有趣的是，来自有纤毛OSN的轴突共同收敛于同一肾小球。尽管肾小球的神经支配在一起，来自纤毛OSN的两个不同子集的轴突和末端区域仍然是单色的。染色后4-6天，将染料反式突触转移至中继神经元的单独染色轴突。这些发现表明，尽管嗅觉肾小球混合神经支配，初级神经元的特异性仍保留在嗅觉途径中。讨论了有关非哺乳动物肾小球新兴概念的结果。

著录项

相似文献

  • 外文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号