Prostate cancer: radical prostatectomy.

Nelson JB; Lepor H

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Prostate cancer: radical prostatectomy.

机译：前列腺癌：前列腺癌根治术。

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Today, more men than ever before are being followed after radical prostatectomy. Prognosis and follow-up should be based on the pathologic specimen. Measurable prostate-specific antigen (PSA) after surgery defines failure, with time to detectable PSA and rate of PSA rise being useful prognostic factors. The natural history of untreated biochemical failure is protracted, a fact to be considered in discussions of adjuvant treatment. Early in disease recurrence, imaging studies to locate residual disease rarely are useful clinically. Both adjuvant and salvage radiation to the prostate bed have benefits and risks, but neither is superior in overall prostate cancer survival. The timing of hormone therapy remains largely empiric. The promise of effective cytotoxic chemotherapy still is greater than its actual benefits, although novel cytostatic agents are being developed. The future management of this disease will improve with better molecular definition of risk and therapeutic response.

机译：如今，前列腺癌根治术后的男性人数比以往任何时候都要多。预后和随访应基于病理标本。手术后可测量的前列腺特异性抗原（PSA）定义了失败，可检测PSA的时间和PSA升高的速度是有用的预后因素。未经治疗的生化衰竭的自然病程很长，在讨论辅助治疗时应考虑这一事实。在疾病复发的早期，很少有影像学研究来定位残留疾病在临床上是有用的。辅助放射线和挽救性放射线对前列腺床都有益处和风险，但在总体前列腺癌生存率方面均不优越。激素治疗的时机在很大程度上仍然是经验性的。尽管正在开发新型的细胞抑制药物，有效的细胞毒性化学疗法的前景仍然大于其实际收益。随着对风险和治疗反应的更好分子定义，该疾病的未来管理将得到改善。

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《The Urologic clinics of North America》 |2003年第4期|共22页
作者
Nelson JB; Lepor H;
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正文语种 eng
中图分类临床医学;
关键词
Prostatectomy; Prostatic Neoplasms; 前列腺切除术; 前列腺肿瘤;

机译：Prostatectomy;Prostatic Neoplasms;前列腺切除术;前列腺肿瘤;

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专利

1. Real time elastography in the diagnosis of prostate cancer: Comparison of preoperative imaging and histology after radical prostatectomy. [élastographie en temps réel pour l'identification du cancer de prostate: Comparaison d'imagerie préopératoire avec l'anatomopathologie après prostatectomie totale] [J] . Progres en urologie: journal de l’Association francaise d’urologie et de la Societefrancaise d’urologie . 2011,第13期

机译：实时弹性成像诊断前列腺癌：前列腺癌根治术后术前影像学和组织学的比较。实时弹性成像技术鉴定前列腺癌的比较：全前列腺切除术后术前影像学与解剖病理学的比较
2. Clinical utility of antioxidant gene expression levels in circulating cancer cell clusters for the detection of prostate cancer in patients with prostate-specific antigen levels of 4-10 ng/mL and disease prognostication after radical prostatectomy. [J] . Giesing M, Suchy B, Driesel G, BJU international . 2010,第7期

机译：循环癌细胞群中抗氧化剂基因表达水平在检测前列腺特异性抗原水平为4-10 ng / mL且进行前列腺癌根治术后疾病预后的患者中检测前列腺癌的临床实用性。
3. Investigative clinical study on prostate cancer part II: on the role of the pretreatment total PSA to free testosterone ratio as a marker assessing prostate cancer prognostic groups after radical retropubic prostatectomy. [J] . Porcaro AB, Monaco C, Romano M, Urologia internationalis . 2010,第2期

机译：前列腺癌的研究性临床研究第二部分：预处理总PSA与游离睾丸激素之比的作用，作为评估耻骨后前列腺切除术后前列腺癌预后组的指标。
4. Framework for the co-registration of MRI and Histology Images in Prostate Cancer Patients with Radical Prostatectomy [C] . Mirabela Rusu, Christian Kunder, Richard Fan, Society of Photo-Optical Instrumentation Engineers;SPIE Medical Imaging Conference . 2019

机译：前列腺癌根治性前列腺切除术患者的MRI和组织学图像共同配准的框架
5. Use of Serum Prostate Specific Antigen Doubling Time and Change to Determine Need for Secondary Treatment for Prostate Cancer following Radical Prostatectomy [D] . Huang, Erica Jayee. 2021

机译：使用血清前列腺特异性抗原的倍增时间和变化，以确定自由基前列腺切除术后前列腺癌的继发性治疗
6. Identification of curable high-risk prostate cancer using radical prostatectomy alone: who are the good candidates for undergoing radical prostatectomy among patients with high-risk prostate cancer? [O] . Kazuhiro Nagao, Hideyasu Matsuyama, Hiroaki Matsumoto, -1

机译：仅使用根治性前列腺切除术就可以确定可治愈的高危前列腺癌：在高危前列腺癌患者中进行根治性前列腺切除术的最佳人选是谁？
7. NADiA ProsVue prostate-specific antigen slope is an independent prognostic marker for identifying men at reduced risk of clinical recurrence of prostate cancer after radical prostatectomy. [O] . Moul, JW, Lilja, H, Semmes, OJ, 2012

机译：NADiA ProsVue前列腺特异性抗原斜率是一项独立的预后标志物，可用于识别根治性前列腺切除术后前列腺癌临床复发风险降低的男性。
8. Prostate Cancer Detection Using High-Spatial Resolution MRI at 7.0 Tesla: Correlation with Histopathologic Findings at Radical Prostatectomy. [R] . Rosenkrantz, A. B. 2012

机译：使用7.0特斯拉的高空间分辨率mRI检查前列腺癌：与根治性前列腺切除术中组织病理学发现的相关性。

Prostate cancer: radical prostatectomy.

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