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首页> 外文期刊>The Urologic clinics of North America >Brachytherapy for prostate cancer: follow-up and management of treatment failures.
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Brachytherapy for prostate cancer: follow-up and management of treatment failures.

机译：前列腺癌的近距离治疗：治疗失败的随访和管理。

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The use of prostate brachytherapy for the treatment of early-stage, low-grade, low-volume carcinoma of the prostate continues to rise. Given the prolonged natural history of these early lesions, treatment failures may take many years or even a decade or more before becoming clinically evident. It is therefore likely that as the brachytherapy data mature, clinicians will be asked to help manage a potentially large cohort of men who have failed this local therapy--a scenario that will provide a number of unique challenges for the treatment of the disease and the management of the lower urinary tract. This article offers a contemporary review and suggestions with regard to the follow-up of patients who have undergone prostate brachytherapy, including low-dose rate permanent implants and high-dose rate temporary implants for the management of localized prostate cancer. In addition, current controversies in defining biochemical failure following radioactive implantation--including important data regarding the prostate-specific antigen bounce comprehensive review of the management of local recurrence following brachytherapy is offered.
机译：前列腺近距离放射疗法在治疗早期，低级，小容量的前列腺癌中的应用继续增加。鉴于这些早期病变的自然病程延长，治疗失败可能需要很多年甚至十年甚至更长的时间才能成为临床证据。因此，随着近距离放射治疗数据的成熟，可能会要求临床医生帮助管理可能无法接受这种局部疗法的大量男性患者，这种情况将为该疾病的治疗和治疗带来许多独特的挑战。下尿路的管理。本文就已接受前列腺近距离放射治疗的患者的随访情况提供了当代的评论和建议，包括低剂量率永久性植入物和高剂量率临时性植入物以治疗局部前列腺癌。此外，目前在定义放射性植入后生化衰竭方面的争议-包括有关前列腺特异性抗原反弹的重要数据，对近距离放射治疗后局部复发的处理进行了全面回顾。

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