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HERPESVIRAL ABORTION IN DOMESTIC ANIMALS [Review]

机译:国内动物的疱疹流产[评论]

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摘要

Abortion or neonatal disease may follow infection with several alpha, beta and gamma-herpesviruses. The alpha-herpesvirus, equid herpesvirus-1 (EHV-1), causes single or epizootic abortions or neonatal deaths in equids, and the closely related virus EHV-4 causes sporadic equine abortions. In cattle, the alpha-herpesviruses, bovine herpesvirus-1 (infectious bovine rhinotracheitis virus) and bovine herpesvirus-5 (bovine encephalitis virus), and a gamma-herpesvirus, bovine herpesvirus-4, have all been implicated as causes of abortion. In pigs, suid herpesvirus-1 (SHV-1: pseudorabies virus), an alpha-herpesvirus, and SHV-2 (porcine cytomegalovirus), a beta-herpesvirus, each cause abortion or neonatal piglet losses. Caprine herpesvirus-1, canine herpesvirus and feline herpesvirus-1, all alpha-herpesviruses, cause abortions or neonatal deaths in goats, dogs and cats, respectively. This review discusses the pathogenesis, pathology and laboratory diagnosis of these herpesviral abortions and neonatal disease, with an emphasis on experimental studies of each disease. Alternative reviews covering other aspects of each infection, such as the genetic and antigenic structure of the viruses, host immune responses and approaches to vaccination and disease control are indicated at appropriate points in the test.
机译:流产或新生儿疾病可能在感染了几种甲型,乙型和丙型疱疹病毒之后。 α-疱疹病毒即马疱疹病毒-1(EHV-1)导致马匹单次或流行性流产或新生儿死亡,而密切相关的病毒EHV-4则导致马的零星流产。在牛中,α-疱疹病毒牛疱疹病毒-1(传染性牛鼻气管炎病毒)和牛疱疹病毒-5(牛脑炎病毒)和伽马疱疹病毒牛疱疹病毒-4都被认为是流产的原因。在猪中,suid疱疹病毒-1(SHV-1:伪狂犬病病毒)(一种α-疱疹病毒)和SHV-2(猪巨细胞病毒)(一种β-疱疹病毒)各自引起流产或新生仔猪损失。山羊疱疹病毒-1,犬疱疹病毒和猫疱疹病毒-1(所有α-疱疹病毒)分别导致山羊,狗和猫的流产或新生儿死亡。这篇综述讨论了这些疱疹病毒流产和新生儿疾病的发病机理,病理学和实验室诊断,重点是每种疾病的实验研究。在测试的适当位置,应注明涉及每种感染其他方面的其他评论,例如病毒的遗传和抗原结构,宿主免疫反应以及疫苗接种和疾病控制的方法。

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