首页> 外文期刊>The Veterinary Journal >In vitro effect of glucocorticoids on phagocytic function of sheepalveolar macrophages
【24h】

In vitro effect of glucocorticoids on phagocytic function of sheepalveolar macrophages

机译:糖皮质激素对绵羊肺泡巨噬细胞吞噬功能的体外作用

获取原文
获取原文并翻译 | 示例
           

摘要

The potentiation of infection is a recognized adverse effect of steroids. This study examined the in vitro effect of glucocorticoids on sheep alveolar macrophage phagocytic function, an essential means of cellular defence in the lungs, by evaluating the phagocytosis of zymosan particles after 30 min of contact between alveolar macrophages and steroids. Hydrocortisone, dexamethasone phosphate and methylprednisolone significantly reduced the phagocytic capability of sheep alveolar macrophages, but the effects of dexamethasone isonicotinate, prednisolone and flumethasone were less marked.
机译:感染的增强是类固醇的公认不良反应。这项研究通过评估肺泡巨噬细胞与类固醇接触30分钟后酵母聚糖颗粒的吞噬作用,研究了糖皮质激素对绵羊肺泡巨噬细胞吞噬功能的体外作用,这是肺部细胞防御的一种重要手段。氢化可的松,磷酸地塞米松和甲基泼尼松龙显着降低了绵羊肺泡巨噬细胞的吞噬能力,​​但地塞米松异烟酸酯,泼尼松龙和氟美松的作用较不明显。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号