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Characteristics of live bovine herpesvirus-1 vaccines

机译:牛疱疹病毒1型活疫苗的特征

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The common disease caused by bovine herpes virus 1 infection is febrile rhinotracheitis (FRT) and under certain conditions the virus is strongly implicated in pre-disposing cattle to pneumonic pasteurellosis. These illnesses account for a significant economic loss in the cattle industry worldwide and vaccination is widely applied. In naive cattle, and for a short period of time, old and new vaccines significantly reduce clinical signs of FRT and also virus shedding. A single intranasal vaccination affords significant protection in face of maternally derived antibodies, and the protection can be significantly prolonged by a booster intramuscular vaccination. Current data recommend vaccination in face of an outbreak and vaccines appear safe for pregnant cattle.
机译:由牛疱疹病毒1感染引起的常见疾病是高热性鼻气管炎(FRT),在某些条件下,该病毒与牛容易患肺巴氏杆菌病有很大关系。这些疾病造成了全世界养牛业的重大经济损失,疫苗接种得到了广泛应用。在幼稚的牛中,在短时间内,新旧疫苗会大大降低FRT的临床体征以及病毒的脱落。面对孕妇来源的抗体,单次鼻内疫苗接种可提供显着的保护,而加强型肌肉内疫苗接种可大大延长保护时间。当前数据建议在爆发时接种疫苗,疫苗对怀孕的牛似乎是安全的。

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