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首页> 外文期刊>The Veterinary Journal >Acute haemostatic changes in accidentally traumatised dogs
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Acute haemostatic changes in accidentally traumatised dogs

机译：意外受伤的狗的急性止血变化

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Alterations of the haemostatic system were studied in 30 dogs within 24 h following natural injury. No other exclusion criteria were considered. Most dogs had bone fractures, thoracic and/or abdominal trauma. Compared to the controls, the platelet count and activities of all individual coagulation factors, inhibitors of the blood coagulation system (antithrombin, protein C) and plasminogen were significantly decreased (P < 0.01). The only exceptions were alpha2-plasmin inhibitor activity, which did not differ from the control group (P > 0.05), and an increased fibrinogen concentration (P = 0.0113). Deficiencies in the coagulation system were reflected by frequent abnormal results of the screening tests. In most of the animals, the concentrations of soluble fibrin and/or fibrin(ogen) degradation products were above the reference values (P < 0.0001). The absence of a decrease in fibrinogen and alpha2-plasmin inhibitor reflects their role as acute phase reactants. The results of this study indicate the high frequency of decompensated consumption of haemostatic components in acutely traumatised dogs.
机译：在自然受伤后24小时内，对30只狗的止血系统进行了研究。没有考虑其他排除标准。大多数狗患有骨折，胸腔和/或腹部外伤。与对照组相比，所有个体凝血因子，凝血系统抑制剂（抗凝血酶，蛋白C）和纤溶酶原的血小板计数和活性均显着降低（P <0.01）。唯一的例外是alpha2-纤溶酶抑制剂活性，与对照组无差异（P> 0.05），纤维蛋白原浓度增加（P = 0.0113）。频繁的筛查结果异常反映了凝血系统的缺陷。在大多数动物中，可溶性血纤蛋白和/或血纤蛋白（原）降解产物的浓度均高于参考值（P <0.0001）。纤维蛋白原和α2-纤溶酶抑制剂的减少没有反映出它们作为急性期反应物的作用。这项研究的结果表明，在遭受严重创伤的狗中，止血成分的失代偿食用频率很高。

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