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Blood-oxygen binding in healthy Standardbred horses

机译：健康标准马匹中的血氧结合

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The purpose of this study was to determine the effect of regulating factors on the oxygen equilibrium curve (OEC) under standard conditions and then to calculate the oxygen extraction between arterial and jugular venous blood in healthy Standardbred horses. The results were compared to those previously obtained in humans and cattle, using the same experimental method. The partial oxygen pressure at 50% saturation of haemoglobin, measured under standard conditions (standard P50), was 24.8+/-2.0 (SD of mean) mmHg. This value was similar to the cattle standard P50 (25.0+/-1.4 mmHg, SD of mean) but lower than the human standard P50 (26.6+/-1.2 mmHg, SD of mean) previously reported using the same experimental method. The effects of regulating factors on the standard OEC were also determined, and a major effect of pH and temperature was noted. In contrast, partial carbon dioxide pressure played only a minor role in horses, compared to cattle and humans. No significant correlation was found between phosphate and chloride concentrations and standard P50.
机译：这项研究的目的是确定标准条件下调节因素对氧气平衡曲线（OEC）的影响，然后计算健康标准马匹中动脉和颈静脉血之间的氧气提取量。使用相同的实验方法，将结果与先前在人和牛中获得的结果进行比较。在标准条件下（标准P50）测得的血红蛋白饱和度为50％时的分氧压为24.8 +/- 2.0（平均标准偏差）mmHg。该值类似于牛标准P50（25.0 +/- 1.4 mmHg，平均值SD），但低于先前使用相同实验方法报道的人标准P50（26.6 +/- 1.2 mmHg，平均值SD）。还确定了调节因子对标准OEC的影响，并注意到了pH和温度的主要影响。相比之下，与牛和人相比，二氧化碳分压在马匹中只发挥了很小的作用。在磷酸盐和氯化物浓度与标准P50之间未发现显着相关性。

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