Challenges in pulmonary fibrosis. 2: Bronchiolocentric fibrosis.

Cordier JF

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Challenges in pulmonary fibrosis. 2: Bronchiolocentric fibrosis.

机译：肺纤维化的挑战。 2：细支气管中心纤维化。

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Bronchiolocentric fibrosis is essentially represented by the pathological pattern of constrictive fibrotic bronchiolitis obliterans. The corresponding clinical condition (obliterative bronchiolitis) is characterised by dyspnoea, airflow obstruction at lung function testing and air trapping with characteristic mosaic features on expiratory high resolution CT scans. Bronchiolitis obliterans may result from many causes including acute diffuse bronchiolar damage after inhalation of toxic gases or fumes, alloimmune chronic processes after lung or haematopoietic stem cell transplantation, or connective tissue disease (especially rheumatoid arthritis). Airway-centred interstitial fibrosis and bronchiolar metaplasia are other features of bronchiolocentric fibrosis.

机译：细支气管纤维化主要表现为闭塞性纤维化闭塞性细支气管炎的病理模式。相应的临床症状（闭塞性细支气管炎）的特征是呼吸困难，肺功能测试时出现气流阻塞以及呼气高分辨率CT扫描上具有特征性镶嵌特征的空气滞留。闭塞性细支气管炎可能由多种原因引起，包括吸入有毒气体或烟气后急性弥漫性细支气管损害，肺或造血干细胞移植后的同种免疫慢性过程或结缔组织疾病（尤其是类风湿性关节炎）。气道中心性间质纤维化和细支气管化生是细支气管中心性纤维化的其他特征。

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《Thorax: The Journal of the British Thoracic Society》 |2007年第7期|共12页
作者
Cordier JF;
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正文语种 eng
中图分类呼吸系及胸部疾病;外科学各论;
关键词
Fibrosis; Pulmonary Fibrosis; Toxic effect; interstitial; 纤维变性; 肺纤维化;

机译：Fibrosis;Pulmonary Fibrosis;Toxic effect;interstitial;纤维变性;肺纤维化;

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1. Challenges in pulmonary fibrosis. 2: Bronchiolocentric fibrosis. [J] . Cordier JF Thorax: The Journal of the British Thoracic Society . 2007,第7期

机译：肺纤维化的挑战。 2：细支气管中心纤维化。
2. Challenges in pulmonary fibrosis. 1: Use of high resolution CT scanning of the lung for the evaluation of patients with idiopathic interstitial pneumonias. [J] . Gotway MB, Freemer MM, King-TE Jr Thorax: The Journal of the British Thoracic Society . 2007,第6期

机译：肺纤维化的挑战。 1：肺部高分辨率CT扫描用于评估特发性间质性肺炎的患者。
3. Challenges in pulmonary fibrosis. 3: Cystic lung disease. [J] . Cosgrove GP, Frankel SK, Brown KK Thorax: The Journal of the British Thoracic Society . 2007,第9期

机译：肺纤维化的挑战。 3：囊性肺疾病。
4. Pulmonary Nodule Detection Techniques in CT Images: New Strategies and Challenges [C] . Chinnu Jacob, C. Gopakumar International Conference on Advanced Computing and Communication Systems . 2020

机译：CT图像中的肺结节检测技术：新策略和新挑战
5. Genomic Phenotype of Pulmonary Fibroblasts in Idiopathic Pulmonary Fibrosis. [D] . Emblom-Callahan, Margaret Claire. 2010

机译：特发性肺纤维化中肺成纤维细胞的基因表型。
6. Increased expression of the interleukin-8 gene by alveolar macrophages in idiopathic pulmonary fibrosis. A potential mechanism for the recruitment and activation of neutrophils in lung fibrosis. [O] . P C Carré, R L Mortenson, T E King Jr, 1991

机译：肺泡巨噬细胞在特发性肺纤维化中白细胞介素8基因的表达增加。肺纤维化中嗜中性粒细胞募集和激活的潜在机制。
7. Increased expression of the interleukin-8 gene by alveolar macrophages in idiopathic pulmonary fibrosis. A potential mechanism for the recruitment and activation of neutrophils in lung fibrosis. [O] . Carré, P C, Mortenson, R L, King, T E, 1991

机译：肺泡巨噬细胞在特发性肺纤维化中白细胞介素8基因的表达增加。肺纤维化中嗜中性粒细胞募集和激活的潜在机制。

Challenges in pulmonary fibrosis. 2: Bronchiolocentric fibrosis.

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