The biology of P-selectin glycoprotein ligand-1: its role as a selectin counterreceptor in leukocyte-endothelial and leukocyte-platelet interaction.

Yang J; Furie BC; Furie B

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The biology of P-selectin glycoprotein ligand-1: its role as a selectin counterreceptor in leukocyte-endothelial and leukocyte-platelet interaction.

机译：P-选择蛋白糖蛋白配体-1的生物学特性：它在白细胞-内皮和白细胞-血小板相互作用中作为选择素抗受体的作用。

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Cell-cell interactions mediating leukocyte trafficking, thrombogenesis and inflammation are crucial for the host defense mechanism. The selectin family of integral membrane proteins includes E-selectin, L-selectin and P-selectin. Selectins mediate tethering and rolling of leukocytes to the vessel wall at the site of inflammation. The counter-receptor for P-selectin and possibly the other selectins is P-selectin glycoprotein ligand-1 (PSGL-1). This review focuses on the properties and biology of PSGL- 1.

机译：介导白细胞运输，血栓形成和炎症的细胞间相互作用对于宿主防御机制至关重要。整合膜蛋白的选择素家族包括E-选择素，L-选择素和P-选择素。选择素介导发炎部位的白细胞束缚和滚动至血管壁。 P-选择蛋白和可能的其他选择蛋白的反受体是P-选择蛋白糖蛋白配体-1（PSGL-1）。这篇综述着重于PSGL-1的特性和生物学。

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《Thrombosis and Haemostasis: Journal of the International Society on Thrombosis and Haemostasis》 |1999年第1期|共7页
作者
Yang J; Furie BC; Furie B;
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正文语种 eng
中图分类心脏、血管（循环系）疾病;神经病学;
关键词
Blood Platelets; Cell Communication; Endothelium; Vascular; Leukocytes; Membrane Glycoproteins; 血小板; 细胞交流; 内皮; 血管; 白细胞; 膜糖蛋白类; P选择素;

机译：Blood Platelets;Cell Communication;Endothelium;Vascular;Leukocytes;Membrane Glycoproteins;血小板;细胞交流;内皮;血管;白细胞;膜糖蛋白类;P选择素;

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1. The biology of P-selectin glycoprotein ligand-1: its role as a selectin counterreceptor in leukocyte-endothelial and leukocyte-platelet interaction. [J] . Yang J, Furie BC, Furie B Thrombosis and Haemostasis: Journal of the International Society on Thrombosis and Haemostasis . 1999,第1期

机译：P-选择蛋白糖蛋白配体-1的生物学特性：它在白细胞-内皮和白细胞-血小板相互作用中作为选择素抗受体的作用。
2. P-selectin glycoprotein ligand-1 inhibition blocks increased leukocyte-endothelial interactions associated with sickle cell disease in mice [J] . LuoW., CampbellA., WangH., Blood: The Journal of the American Society of Hematology . 2012,第18期

机译：P-选择蛋白糖蛋白配体-1抑制作用抑制小鼠镰状细胞病相关的白细胞-内皮相互作用
3. Role of P-selectin and P-selectin glycoprotein ligand-1 interaction in the induction of tissue factor expression on human platelets after incubation with porcine aortic endothelial cells (vol 21, pg 16, 2014) [J] . Ezzelarab M. B., Liu Y. W., Lin C. C. Xenotransplantation . 2015,第1期

机译：与猪主动脉内皮细胞孵育后，P-选择蛋白和P-选择蛋白糖蛋白配体1相互作用在诱导人血小板中组织因子表达中的作用（第21卷，第16页，2014年）
4. Platelets Amplify the Fcg-Receptor Triggered Neutrophil Respiratory Burst at Non-Phagosytosable Surfaces:-A Role for P-Selectin Glycoprotein Ligand-1 (PSGL-1; CD162) [C] . Jonas Wetter?, Pentti Tengvall, Torbj?rn Bengtsson Annual meeting of the Society For Biomaterials . 2002

机译：血小板在非吞噬作用的表面上放大Fcg受体触发的中性粒细胞呼吸爆发：-P-选择蛋白糖蛋白配体1（PSGL-1; CD162）的作用
5. Direct comparison of P-selectin Glycoprotein Ligand-1 and Sialyl Lewis x adhesion. [D] . Zou, Xiaoyan. 2008

机译：P-选择蛋白糖蛋白配体1和唾液酸化Lewis X粘附力的直接比较。
6. Hemostasis Thrombosis and Vascular Biology: An L-selectin ligand distinct from P-selectin glycoprotein ligand-1 is expressed on endothelial cells and promotes neutrophil rolling in inflammation [O] . Akiko Shigeta, Masanori Matsumoto, Thomas F. Tedder, -1

机译：止血血栓形成和血管生物学：与P-选择蛋白糖蛋白配体-1不同的L-选择蛋白配体在内皮细胞上表达并促进炎症中的中性粒细胞滚动
7. Redistribution of P-selectin glycoprotein ligand-1 (PSGL-1) in chemokine-treated neutrophils: a role of lipid microdomains [O] . 2014

机译：p-选择素糖蛋白配体-1（psGL-1）在趋化因子处理的中性粒细胞中的重新分布：脂质微区的作用

The biology of P-selectin glycoprotein ligand-1: its role as a selectin counterreceptor in leukocyte-endothelial and leukocyte-platelet interaction.

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