Fibrin clot formation and fibrinolysis in patients with a history of coronary stent thrombosis

Godschalk Thea C.; Konings Joke; Govers-Riemslag Jose W.; ten Berg Jurrien M.; Hackeng Christian M.; ten Cate Hugo

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Fibrin clot formation and fibrinolysis in patients with a history of coronary stent thrombosis

机译：有冠状动脉支架血栓形成史的患者血纤蛋白凝块形成和纤维蛋白溶解

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Introduction: Coronary stent thrombosis is a devastating complication of percutaneous coronary intervention (PCI). Multiple factors underlie the pathophysiological mechanisms of stent thrombosis. Previous studies demonstrated that patients with stent thrombosis, compared to control PCI patients, formed denser fibrin clots in vitro which were more resistant to fibrinolysis, suggesting that altered fibrin clot properties may contribute to the pathophysiology of stent thrombosis. We assessed the plasma fibrin clot formation and fibrinolysis of patients with and without stent thrombosis.

机译：简介：冠状动脉支架血栓形成是经皮冠状动脉介入治疗（PCI）的毁灭性并发症。支架血栓形成的病理生理机制是多种因素的基础。先前的研究表明，与对照组的PCI患者相比，具有支架血栓形成的患者在体外形成了更致密的血纤蛋白凝块，对血纤蛋白溶解更具抵抗力，这表明血纤蛋白凝块特性的改变可能有助于支架血栓形成的病理生理。我们评估了有或没有支架血栓形成的患者血浆纤维蛋白凝块的形成和纤维蛋白溶解。

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来源
《Thrombosis Research: An International Journal on Vascular Obstruction, Hemorrhage and Hemostasis》 |2016年第null期|共5页
作者
Godschalk Thea C.; Konings Joke; Govers-Riemslag Jose W.; ten Berg Jurrien M.; Hackeng Christian M.; ten Cate Hugo;
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正文语种 eng
中图分类神经病学;
关键词
Coronary thrombosis; Fibrin; Fibrinolysis; Percutaneous coronary intervention; Stent;

机译：冠状动脉血栓形成;纤维蛋白;纤溶;经皮冠状动脉介入治疗;支架;

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1. Fibrin clot formation and fibrinolysis in patients with a history of coronary stent thrombosis [J] . Godschalk Thea C., Konings Joke, Govers-Riemslag Jose W., Thrombosis Research: An International Journal on Vascular Obstruction, Hemorrhage and Hemostasis . 2016,第Null期

机译：有冠状动脉支架血栓形成史的患者血纤蛋白凝块形成和纤维蛋白溶解
2. A novel simultaneous clot‐fibrinolysis waveform analysis for assessing fibrin formation and clot lysis in haemorrhagic disorders [J] . Nogami Keiji, Matsumoto Tomoko, Sasai Kana, British Journal of Haematology . 2019,第4期

机译：一种用于评估纤维蛋白形成和出血性疾病凝块裂解的新型凝块 - 纤维蛋白解波形分析
3. Reduced Thrombin Formation and Altered Fibrin Clot Properties Induced by Polyunsaturated Omega-3 Fatty Acids on Top of Dual Antiplatelet Therapy in Patients Undergoing Percutaneous Coronary Intervention (OMEGA-PCI Clot). [J] . Gajos G, Zalewski J, Rostoff P, Arteriosclerosis, thrombosis, and vascular biology . 2011,第7期

机译：经皮冠状动脉介入治疗（OMEGA-PCI凝块）的患者在双重抗血小板治疗的基础上，通过多不饱和Omega-3脂肪酸诱导的凝血酶形成减少和纤维蛋白凝块性质改变。
4. Stent Thrombosis After Primary Percutaneous Coronary Intervention in Real World Patients [C] . Gomez I, Jimenez V, Baz JA, International Congress on Coronary Artery Disease . 2011

机译：在现实世界患者中初次经皮冠状动脉干预后支架血栓形成
5. The role of different cell types on thrombin generation and fibrin clot formation and structure. [D] . Campbell, Robert A. 2009

机译：不同细胞类型对凝血酶生成和纤维蛋白凝块形成与结构的作用。
6. Predictive value of C-reactive protein for radiographic spinal progression in axial spondyloarthritis in dependence on genetic determinants of fibrin clot formation and fibrinolysis [O] . Berthold Hoppe, Christian Schwedler, Hildrun Haibel, 2021

机译：纤维蛋白凝块形成和纤维蛋白分解遗传决定因素C-脊髓关节炎基脊髓关节炎C-反应蛋白的预测值
7. A novel simultaneous clot‐fibrinolysis waveform analysis for assessing fibrin formation and clot lysis in haemorrhagic disorders [O] . Keiji Nogami, Tomoko Matsumoto, Kana Sasai, 2019

机译：一种用于评估纤维蛋白形成和出血性疾病凝块裂解的新型凝块 - 纤维蛋白解波形分析

Fibrin clot formation and fibrinolysis in patients with a history of coronary stent thrombosis

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